Invasive candidiasis caused by the pathogenic Candida yeast species has resulted in
elevating global mortality. The pathogenicity of Candida spp. is not only originated from its …

Invasive fungal diseases (IFDs) comprise a growing healthcare burden, especially given the
expanding population of immunocompromised hosts. Early diagnosis of IFDs is required to …

The overexpression of genes frequently arises in Nakaseomyces (formerly Candida)
glabrata via gain-of-function mutations, gene duplication, or aneuploidies, with important …

Clustered regularly interspaced short palindromic repeats (CRISPR) has revolutionized the
field of genome editing. To circumvent the permanent modifications made by traditional …

Catheter-associated urinary tract infections (CAUTIs) account for 40% of hospital-acquired
infections (HAIs). As 20 to 50% of hospitalized patients receive catheters, CAUTIs are one of …

The spread of multi-drug-resistant (MDR) pathogens has rapidly outpaced the development
of effective treatments. Diverse resistance mechanisms further limit the effectiveness of our …

Although fungi have been important model organisms for solving genetic, molecular, and
ecological problems, recently, they are also becoming an important source of infectious …

Years ago, I attended a seminar by John Carbon, who played a key early role in developing
molecular genetics tools in the budding yeast Saccharomyces cerevisiae and in identifying …

Antimicrobial-induced DNA damage, and subsequent repair via upregulation of DNA repair
factors, including error-prone translesion polymerases, can lead to the increased …

The overexpression of genes frequently arises in Nakeseomyces (formerly Candida)
glabrata via gain-of-function mutations, gene duplication or aneuploidies, with important …