Bibliometric analysis and thematic review of Candida pathogenesis: Fundamental omics to applications as potential antifungal drugs and vaccines
Invasive candidiasis caused by the pathogenic Candida yeast species has resulted in
elevating global mortality. The pathogenicity of Candida spp. is not only originated from its …
elevating global mortality. The pathogenicity of Candida spp. is not only originated from its …
Molecular Diagnostics for Invasive Fungal Diseases: Current and Future Approaches
D Pham, V Sivalingam, HM Tang, JM Montgomery… - Journal of Fungi, 2024 - mdpi.com
Invasive fungal diseases (IFDs) comprise a growing healthcare burden, especially given the
expanding population of immunocompromised hosts. Early diagnosis of IFDs is required to …
expanding population of immunocompromised hosts. Early diagnosis of IFDs is required to …
Functional genetic characterization of stress tolerance and biofilm formation in Nakaseomyces (Candida) glabrata via a novel CRISPR activation system
L Maroc, H Shaker, RS Shapiro - Msphere, 2024 - Am Soc Microbiol
The overexpression of genes frequently arises in Nakaseomyces (formerly Candida)
glabrata via gain-of-function mutations, gene duplication, or aneuploidies, with important …
glabrata via gain-of-function mutations, gene duplication, or aneuploidies, with important …
The rise and future of CRISPR-based approaches for high-throughput genomics
S Vercauteren, S Fiesack, L Maroc… - FEMS Microbiology …, 2024 - academic.oup.com
Clustered regularly interspaced short palindromic repeats (CRISPR) has revolutionized the
field of genome editing. To circumvent the permanent modifications made by traditional …
field of genome editing. To circumvent the permanent modifications made by traditional …
The catheterized bladder environment promotes Efg1- and Als1-dependent Candida albicans infection
AA La Bella, MJ Andersen, NC Gervais, JJ Molina… - Science …, 2023 - science.org
Catheter-associated urinary tract infections (CAUTIs) account for 40% of hospital-acquired
infections (HAIs). As 20 to 50% of hospitalized patients receive catheters, CAUTIs are one of …
infections (HAIs). As 20 to 50% of hospitalized patients receive catheters, CAUTIs are one of …
Blunted blades: new CRISPR-derived technologies to dissect microbial multi-drug resistance and biofilm formation
C Gager, AL Flores-Mireles - Msphere, 2024 - Am Soc Microbiol
The spread of multi-drug-resistant (MDR) pathogens has rapidly outpaced the development
of effective treatments. Diverse resistance mechanisms further limit the effectiveness of our …
of effective treatments. Diverse resistance mechanisms further limit the effectiveness of our …
Advanced genetic techniques in fungal pathogen research
RL Ross, FH Santiago-Tirado - Msphere, 2024 - Am Soc Microbiol
Although fungi have been important model organisms for solving genetic, molecular, and
ecological problems, recently, they are also becoming an important source of infectious …
ecological problems, recently, they are also becoming an important source of infectious …
The micromammals
SL Forsburg - G3 Genes| Genomes| Genetics, 2024 - academic.oup.com
Years ago, I attended a seminar by John Carbon, who played a key early role in developing
molecular genetics tools in the budding yeast Saccharomyces cerevisiae and in identifying …
molecular genetics tools in the budding yeast Saccharomyces cerevisiae and in identifying …
A role for the putative error-prone polymerase REV1 in DNA damage and antifungal drug resistance in Candida albicans
MR Agyare-Tabbi, D Uthayakumar, D Francis, L Maroc… - bioRxiv, 2024 - biorxiv.org
Antimicrobial-induced DNA damage, and subsequent repair via upregulation of DNA repair
factors, including error-prone translesion polymerases, can lead to the increased …
factors, including error-prone translesion polymerases, can lead to the increased …
Functional genetic characterization of stress tolerance and biofilm formation in Nakaseomyces glabrata via a novel CRISPR activation system
L Maroc, H Shaker, RS Shapiro - bioRxiv, 2023 - biorxiv.org
The overexpression of genes frequently arises in Nakeseomyces (formerly Candida)
glabrata via gain-of-function mutations, gene duplication or aneuploidies, with important …
glabrata via gain-of-function mutations, gene duplication or aneuploidies, with important …