[HTML][HTML] Epigenetic regulation of m6A modifications in human cancer
W Zhao, X Qi, L Liu, S Ma, J Liu, J Wu - Molecular Therapy-Nucleic Acids, 2020 - cell.com
N6-methyladenosine (m 6 A) is the most prevalent internal RNA modification, especially
within eukaryotic messenger RNAs (mRNAs). m 6 A modifications of RNA regulate splicing …
within eukaryotic messenger RNAs (mRNAs). m 6 A modifications of RNA regulate splicing …
Biological roles and mechanisms of circular RNA in human cancers
Q Tang, SS Hann - OncoTargets and therapy, 2020 - Taylor & Francis
Circular RNA (circRNA) is an intriguing class of RNA with covalently closed-loop structure
and is highly stable and conservative. As new members of the ncRNAs, the function …
and is highly stable and conservative. As new members of the ncRNAs, the function …
[HTML][HTML] Circular RNA circRNF20 promotes breast cancer tumorigenesis and Warburg effect through miR-487a/HIF-1α/HK2
L Cao, M Wang, Y Dong, B Xu, J Chen, Y Ding… - Cell death & …, 2020 - nature.com
Compelling evidence has demonstrated the potential functions of circular RNAs (circRNAs)
in breast cancer (BC) tumorigenesis. Nevertheless, the underlying mechanism by which …
in breast cancer (BC) tumorigenesis. Nevertheless, the underlying mechanism by which …
N6-methyladenosine METTL3 promotes the breast cancer progression via targeting Bcl-2
H Wang, B Xu, J Shi - Gene, 2020 - Elsevier
Abstract N6-methyladenosine (m6A) is the most prevalent internal modification in
mammalian mRNAs and methyltransferase-like 3 (METTL3) is a vital methyltransferase in …
mammalian mRNAs and methyltransferase-like 3 (METTL3) is a vital methyltransferase in …
Mesenchymal stem cell-originated exosomal circDIDO1 suppresses hepatic stellate cell activation by miR-141-3p/PTEN/AKT pathway in human liver fibrosis
L Ma, J Wei, Y Zeng, J Liu, E Xiao, Y Kang, Y Kang - Drug delivery, 2022 - Taylor & Francis
Liver fibrosis is a common pathologic stage of the development of liver failure. It has showed
that exosomes loaded with therapeutic circRNAs can be manufactured in bulk by exosome …
that exosomes loaded with therapeutic circRNAs can be manufactured in bulk by exosome …
[HTML][HTML] m6A demethylase FTO promotes hepatocellular carcinoma tumorigenesis via mediating PKM2 demethylation
J Li, L Zhu, Y Shi, J Liu, L Lin… - American journal of …, 2019 - ncbi.nlm.nih.gov
Abstract N6-methyladenosine (m6A) acts as the most common mRNA modification in
mammal cells. Fat Mass and Obesity-associated protein (FTO) is the firstly identified …
mammal cells. Fat Mass and Obesity-associated protein (FTO) is the firstly identified …
[HTML][HTML] Splicing factor derived circular RNA circUHRF1 accelerates oral squamous cell carcinoma tumorigenesis via feedback loop
W Zhao, Y Cui, L Liu, X Qi, J Liu, S Ma, X Hu… - Cell Death & …, 2020 - nature.com
Emerging evidences have suggested the vital roles of circular RNA (circRNA) in the human
cancers. However, the underlying biological functions and biogenesis of circRNA in the oral …
cancers. However, the underlying biological functions and biogenesis of circRNA in the oral …
[HTML][HTML] Circular RNA, the key for translation
AC Prats, F David, LH Diallo, E Roussel, F Tatin… - International journal of …, 2020 - mdpi.com
It was thought until the 1990s that the eukaryotic translation machinery was unable to
translate a circular RNA. However internal ribosome entry sites (IRESs) and m6A-induced …
translate a circular RNA. However internal ribosome entry sites (IRESs) and m6A-induced …
[HTML][HTML] Circular RNA circ0005276 promotes the proliferation and migration of prostate cancer cells by interacting with FUS to transcriptionally activate XIAP
Y Feng, Y Yang, X Zhao, Y Fan, L Zhou, J Rong… - Cell death & …, 2019 - nature.com
Prostate cancer (PCa) is one of the major men's malignancies with high mortality worldwide.
Circular RNAs (circRNAs) have been shown to serve as essential regulators in human …
Circular RNAs (circRNAs) have been shown to serve as essential regulators in human …
[HTML][HTML] Steroid-induced osteonecrosis of the femoral head: novel insight into the roles of bone endothelial cells in pathogenesis and treatment
C Huang, Z Wen, J Niu, S Lin, W Wang - Frontiers in cell and …, 2021 - frontiersin.org
Steroid-induced osteonecrosis of the femoral head (SONFH) is a disease characterized by
the collapse of the femoral head. SONFH occurs due to the overuse of glucocorticoids (GCs) …
the collapse of the femoral head. SONFH occurs due to the overuse of glucocorticoids (GCs) …