Malaria is a global infectious disease that remains a leading cause of morbidity and mortality
in the developing world. Multiple environmental and host and parasite factors govern the …

Multiplicity of infection (MOI), also termed complexity of infection (COI), is defined as the
number of genetically distinct parasite strains co-infecting a single host, which is an …

Background Plasmodium parasites undergo several major developmental transitions during
their complex lifecycle, which are enabled by precisely ordered gene expression programs …

Background Deep sequencing of targeted genomic regions is becoming a common tool for
understanding the dynamics and complexity of Plasmodium infections, but its lower limit of …

Simple Summary Malaria is one of the most severe life-threatening human vector-borne
diseases worldwide today, leading to high mortality. Children under the age of five and …

Malaria infection during pregnancy, caused by the sequestering of Plasmodium falciparum
parasites in the placenta, leads to high infant mortality and maternal morbidity. The parasite …

Cerebral malaria (CM) is the severest form of Plasmodium falciparum infection. Children
under 5 years old are those most vulnerable to CM, and they consequently have the highest …

Unprecedented efforts in malaria control over the last 15 years have led to a substantial
decrease in both morbidity and mortality in most endemic settings. However, these …

The human malaria parasite, Plasmodium falciparum, is a unicellular protozoan responsible
for over half a million deaths annually. With a complex life cycle alternating between human …

Molecular surveillance of antimalarial drug resistance markers has become an important
part of resistance detection and containment. In the current climate of multidrug resistance …