Technological advancements in cancer diagnostics: Improvements and limitations

A Pulumati, A Pulumati, BS Dwarakanath… - Cancer …, 2023 - Wiley Online Library
Background Cancer is characterized by the rampant proliferation, growth, and infiltration of
malignantly transformed cancer cells past their normal boundaries into adjacent tissues. It is …

In vivo imaging of human neuroinflammation

DS Albrecht, C Granziera, JM Hooker… - ACS chemical …, 2016 - ACS Publications
Neuroinflammation is implicated in the pathophysiology of a growing number of human
disorders, including multiple sclerosis, chronic pain, traumatic brain injury, and amyotrophic …

Bimodal fluorescence-magnetic resonance contrast agent for apoptosis imaging

H Li, G Parigi, C Luchinat, TJ Meade - Journal of the American …, 2019 - ACS Publications
Effective cancer therapy largely depends on inducing apoptosis in cancer cells via
chemotherapy and/or radiation. Monitoring apoptosis in real-time provides invaluable …

The beginning of the end for conventional RECIST—novel therapies require novel imaging approaches

M Gerwing, K Herrmann, A Helfen… - Nature reviews Clinical …, 2019 - nature.com
Owing to improvements in our understanding of the biological principles of tumour initiation
and progression, a wide variety of novel targeted therapies have been developed …

Fidelity-oriented fluorescence imaging probes for beta-galactosidase: From accurate diagnosis to precise treatment

B Feng, F Chu, A Bi, X Huang, Y Fang, M Liu… - Biotechnology …, 2023 - Elsevier
Abstract Beta-galactosidase (β-gal), a typical glycosidase catalyzing the hydrolysis of
glycosidic bonds, is regarded as a vital biomarker for cell senescence and cancer …

A Magnetically and Electrically Powered Hybrid Micromotor in Conductive Solutions: Synergistic Propulsion Effects and Label‐Free Cargo Transport and Sensing

Y Wu, S Yakov, A Fu, G Yossifon - Advanced Science, 2023 - Wiley Online Library
Electrically powered micro‐and nanomotors are promising tools for in vitro single‐cell
analysis. In particular, single cells can be trapped, transported, and electroporated by a …

Matrine induces Akt/mTOR signalling inhibition‐mediated autophagy and apoptosis in acute myeloid leukaemia cells

J Wu, G Hu, Y Dong, R Ma, Z Yu, S Jiang… - Journal of cellular …, 2017 - Wiley Online Library
Pharmacological modulation of autophagy has been referred to as a promising therapeutic
strategy for cancer. Matrine, a main alkaloid extracted from Sophora flavescens Ait, has …

Nuclear Imaging of Glucose Metabolism: Beyond 18F‐FDG

H Feng, X Wang, J Chen, J Cui, T Gao… - Contrast media & …, 2019 - Wiley Online Library
Glucose homeostasis plays a key role in numerous fundamental aspects of life, and its
dysregulation is associated with many important diseases such as cancer. The atypical …

Designing of various biosensor devices for determination of apoptosis: A comprehensive review

R Akçapınar, B Garipcan, V Goodarzi, L Uzun - … and Biophysical Research …, 2021 - Elsevier
Apoptosis is a type of cell death caused by the occurrence of both pathological and
physiological conditions triggered by ligation of death receptors outside the cell or triggered …

Mechanistic studies of in vitro anti-proliferative and anti-inflammatory activities of the Zn (ii)–NSAID complexes of 1, 10-phenanthroline-5, 6-dione in MDA-MB-231 …

J Deb, TR Lakshman, I Ghosh, SS Jana… - Dalton Transactions, 2020 - pubs.rsc.org
Two zinc (II)–NSAID complexes [(phendione) ZnII (NPR) 2 (H2O) 2](1) and [(phendione) ZnII
(MFN) 2](2)(HNPR= naproxen and HMFN= mefenamic acid) of 1, 10-phenanthroline-5, 6 …