Normal cells produce adenosine 5′-triphosphate (ATP) mainly through mitochondrial
oxidative phosphorylation (OXPHOS) when oxygen is available. Most cancer cells, on the …

In vivo imaging, which enables us to peer deeply within living subjects, is producing
tremendous opportunities both for clinical diagnostics and as a research tool. Contrast …

The prominence of photodynamic therapy (PDT) in treating superficial skin cancer inspires
innovative solutions for its congenitally deficient shadow penetration of the visible-light …

Radiotherapy plays a central part in curing cancer. For decades, most research on
improving treatment outcomes has focused on modulating radiation-induced biological …

Radiation therapy is one of the major tools of cancer treatment, and is widely used for a
variety of malignant tumours. Radiotherapy causes DNA damage directly by ionization or …

Metastasis is not the result of a random event, as cancer cells can sustain and proliferate
actively only in a suitable tissue microenvironment and then form metastases. Since Dr …

Hypoxia‐inducible factor 1 (HIF‐1) is a transcriptional activator of various genes related to
cellular adaptive responses to hypoxia. Dysfunctions in the regulatory systems of HIF‐1 …

Radiotherapy (RT) is a widely explored clinical modality to combat cancer. However, its
therapeutic efficacy is not always satisfied because of the severe hypoxic microenvironment …

Rapidly growing malignant tumors frequently encounter hypoxia and nutrient (eg, glucose)
deprivation, which occurs because of insufficient blood supply. This results in necrotic cell …

Highly sensitive and specific non-invasive molecular imaging methods are particularly
desirable for the early detection of cancers. Here we report a near-infrared optical imaging …