Abstract Background Clostridioides (Clostridium) difficile is an important pathogen of
healthcare-associated diarrhea, however, an increase in the occurrence of C. difficile …

Clostridium difficile epidemiology has changed in recent years, with the emergence of highly
virulent types associated with severe infections, high rates of recurrences and mortality …

Metronidazole was until recently used as a first-line treatment for potentially life-threatening
Clostridioides difficile (CD) infection. Although cases of metronidazole resistance have been …

Clostridium difficile (C. difficile) is the most prevalent causative pathogen of healthcare-
associated diarrhea. Notably, over the past 10 years, the number of Clostridium difficile …

The rapid evolution of antibiotic resistance in Clostridium difficile and the consequent effects
on prevention and treatment of C. difficile infections (CDIs) are matter of concern for public …

The prevalence of Clostridium difficile infections has increased due to the emergence of
epidemic variants from diverse genetic lineages. Here we describe the emergence of a …

We investigated epidemiologic and molecular characteristics of healthcare-associated (HA)
and community-associated (CA) Clostridioides difficile infection (CDI) among adult patients …

Clostridium difficile is an emerging pathogen for humans and animals and there is concern
about the possibility that livestock might serve as a reservoir of epidemic strains. In Spain …

Antibiotic resistance is a major concern in Clostridium difficile, the causative agent of
antibiotic-associated diarrhea. Reduced susceptibility to first-and second-line agents is …

One hundred thirty-three Clostridium difficile strains were collected from 71 patients and
analyzed for the presence of C. difficile toxin B by the cell cytotoxicity neutralization assay …