Remodelers of the vascular microenvironment: The effect of biopolymeric hydrogels on vascular diseases

M Li, M Jin, H Yang - International Journal of Biological Macromolecules, 2024 - Elsevier
Vascular disease is the leading health problem worldwide. Vascular microenvironment
encompasses diverse cell types, including those within the vascular wall, blood cells …

[HTML][HTML] The gasdermin family: emerging therapeutic targets in diseases

C Zhu, S Xu, R Jiang, Y Yu, J Bian, Z Zou - Signal Transduction and …, 2024 - nature.com
The gasdermin (GSDM) family has garnered significant attention for its pivotal role in
immunity and disease as a key player in pyroptosis. This recently characterized class of pore …

[HTML][HTML] Pro-ferroptotic signaling promotes arterial aging via vascular smooth muscle cell senescence

DY Sun, WB Wu, JJ Wu, Y Shi, JJ Xu… - Nature …, 2024 - nature.com
Senescence of vascular smooth muscle cells (VSMCs) contributes to aging-related
cardiovascular diseases by promoting arterial remodelling and stiffness. Ferroptosis is a …

[HTML][HTML] The Potential Involvement of Glycocalyx Disruption in Abdominal Aortic Aneurysm Pathogenesis

B Rabia, S Thanigaimani, J Golledge - Cardiovascular Pathology, 2024 - Elsevier
Background Abdominal aortic aneurysm (AAA) is a weakening and expansion of the
abdominal aorta. Currently, there is no drug treatment to limit AAA growth. The glycocalyx …

Therapeutic potential of natural products and underlying targets for the treatment of aortic aneurysm

W Zhao, B Li, J Hao, R Sun, P He, H Lv, M He… - Pharmacology & …, 2024 - Elsevier
Aortic aneurysm is a vascular disease characterized by irreversible vasodilatation that can
lead to dissection and rupture of the aortic aneurysm, a life-threatening condition. Thoracic …

Systematic review examining the association of angiotensin converting enzyme inhibitor and angiotensin receptor blocker prescription with abdominal aortic …

K Tian, S Thanigaimani, K Gibson… - European Journal of …, 2024 - Elsevier
Objective Whether angiotensin II blockade is an effective medical treatment for abdominal
aortic aneurysms (AAAs) has not been established. This systematic review and meta …

[HTML][HTML] Unveiling the dual role of autophagy in vascular remodelling and its related diseases

H Ren, R Dai, WNN Nabil, Z Xi, F Wang, H Xu - Biomedicine & …, 2023 - Elsevier
Vascular remodelling is an adaptive response to physiological and pathological stimuli that
leads to structural and functional changes in the vascular intima, media, and adventitia …

[HTML][HTML] Neutrophil Extracellular Traps in Cardiovascular and Aortic Disease: A Narrative Review on Molecular Mechanisms and Therapeutic Targeting

N Ibrahim, W Eilenberg, C Neumayer… - International Journal of …, 2024 - mdpi.com
Neutrophil extracellular traps (NETs), composed of DNA, histones, and antimicrobial
proteins, are released by neutrophils in response to pathogens but are also recognized for …

The future for the therapeutics of abdominal aortic aneurysm: engineered nanoparticles drug delivery for abdominal aortic aneurysm

P Du, Y Hou, C Su, J Gao, Y Yang, J Zhang… - … in Bioengineering and …, 2024 - frontiersin.org
Abdominal aortic aneurysm (AAA) is a severe cardiovascular disease with a high mortality
rate. Several screening and diagnostic methods have been developed for AAA early …

Focus on translational vascular biology: new therapeutic targets in hypertension, aortic aneurysm, and atherosclerosis

F Crea - European Heart Journal, 2023 - academic.oup.com
'Balloon pulmonary angioplasty for chronic thromboembolic pulmonary hypertension: a
Clinical Consensus Statement of the ESC Working Group on Pulmonary Circulation and …