[HTML][HTML] Discontinuation of psychotropic medication: a synthesis of evidence across medication classes

CH Vinkers, RW Kupka, BW Penninx, HG Ruhé… - Molecular …, 2024 - nature.com
Pharmacotherapy is an effective treatment modality across psychiatric disorders.
Nevertheless, many patients discontinue their medication at some point. Evidence-based …

Discontinuation symptoms of antidepressants

G Lewis, G Lewis - The Lancet Psychiatry, 2024 - thelancet.com
The presence of discontinuation symptoms when patients stop taking antidepressants has
sparked heated discussion, both on social media and in the general public press. In the …

[HTML][HTML] Social media group support for antidepressant deprescribing: a mixed-methods survey of patient experiences

A Coe, N Abid, C Kaylor-Hughes - Australian Journal of Primary …, 2024 - CSIRO Publishing
Background Antidepressant use has continually increased in recent decades and although
they are an effective treatment for moderate-to-severe depression, when there is no longer a …

Establishing core symptoms of acute serotonin reuptake inhibitor withdrawal: results from an international survey of online peer-support communities

B Shapiro, E Kramer, D Khoury, A Preda - Pharmacopsychiatry, 2023 - thieme-connect.com
Background Serotonin reuptake inhibitor (SRI) antidepressants are commonly associated
with withdrawal reactions. The Discontinuation Emergent Signs and Symptoms (DESS) …

Association between duration of antidepressant treatment for major depressive disorder and relapse rate after discontinuation: A meta-analysis

Y Hu, H Xue, X Ni, Z Guo, L Fan, W Du - Psychiatry Research, 2024 - Elsevier
The optimal duration of antidepressant treatment for patients with major depressive disorder
to reduce the risk of relapse after discontinuation remains uncertain. Medline, Cochrane …

[HTML][HTML] Prevalence, trends, and individual patterns of long-term antidepressant medication use in the adult Swiss general population

MA Amrein, MP Hengartner, M Näpflin… - European Journal of …, 2023 - Springer
Purpose Antidepressant use has increased in many European countries, mostly driven by
longer treatment duration. The aim of this study was to provide prevalence rates of long-term …

The lived experience of withdrawal from Selective Serotonin Reuptake Inhibitor (SSRI) antidepressants: A qualitative interview study

R Mahmood, V Wallace, N Wiles, D Kessler… - Health …, 2024 - Wiley Online Library
Background Our knowledge of the broader impacts of antidepressant withdrawal, beyond
physical side effects, is limited. Further research is needed to investigate the lived …

Understanding Australian general practice patients' decisions to deprescribe antidepressants in the WiserAD trial: a realist informed approach

A Coe, J Gunn, Z Allnutt, C Kaylor-Hughes - BMJ open, 2024 - bmjopen.bmj.com
Objectives To evaluate how an approach to antidepressant deprescribing works, for whom,
and in what contexts by (1) examining the experiences and perceptions of the approach for …

[HTML][HTML] The nature and impact of antidepressant withdrawal symptoms and proposal of the Discriminatory Antidepressant Withdrawal Symptoms Scale (DAWSS)

J Moncrieff, J Read, MA Horowitz - Journal of Affective Disorders Reports, 2024 - Elsevier
Background We sought to understand more about the nature and possible consequences of
antidepressant withdrawal. Methods We surveyed members of 20 peer-led, online groups …

Managing withdrawal symptoms using tapering strips.

PC Groot, J van Os - British Journal of General Practice, 2023 - search.ebscohost.com
Tapering strips and stabilisation strips can also be prescribed to and used by patients in the
UK (www. taperingstrip. com). In their acclaimed article, Palmer and colleagues question …