Atherothrombotic stroke represents approximately 20% of all ischemic strokes. It is caused
by large-artery atherosclerosis, mostly in the internal carotid artery, and it is associated with …

Atherosclerosis remains a leading cause of cardiovascular diseases. Although the
mechanism for atherosclerosis is complex and has not been fully understood, inflammation …

Asymptomatic atherosclerosis begins early in life and may progress in a sex-specific manner
to become the major cause of cardiovascular morbidity and death. As diagnostic tools to …

Atherosclerosis is a generalized and progressive disease. Ageing is a key risk factor for
atherosclerosis progression that is associated with the increased incidence of ischemic …

MicroRNAs are small non-coding post-translational biomolecules which, when expressed,
modify their target genes. It is estimated that microRNAs regulate production of …

Background Despite the widespread use of classical cholesterol-lowering drugs to mitigate
the adverse impacts of dyslipidaemia on atherosclerosis, many patients still face a …

Intracranial and extracranial large-artery atherosclerosis (LAA) are a main cause of ischemic
stroke. Biomarkers may aid in the diagnosis of LAA and help to stratify patients' risk of stroke …

Inflammation has a critical role in the development and progression of atherosclerosis. On
the molecular level, inflammatory pathways negatively impact endothelial barrier properties …

Noncoding RNAs (ncRNAs) are pivotal for various pathological processes, impacting
disease progression. The potential for leveraging ncRNAs to prevent or treat atherosclerosis …

Objective MicroRNA (miR)-22-3p is expressed in atherosclerosis (AS), but its function and
regulatory mechanisms remain unclear. Therefore, the effects of miR-22-3p in AS were …