Hmgcs2 regulates M2 polarization of macrophages to repair myocardial injury induced by sepsis

Z Han, Z Quan, S Zeng, L Wen, H Wang - IJC Heart & Vasculature, 2024 - Elsevier

Sepsis-induced cardiomyopathy (SIC) is a common and high-mortality complication among
critically ill patients. Uncertainties persist regarding the pathogenesis, pathophysiology, and …

1, 25 (OH) 2D3 alleviates oxidative stress and inflammation through up-regulating HMGCS2 in DSS-induced colitis

HQ Wang, MX Zhao, SC Hong, X He, L Tao… - International …, 2023 - Elsevier

Background Previous study found that supplements with active vitamin D3 alleviated
experimental colitis. The objective of this study was to investigate the possible role of 3 …

[HTML][HTML] PPARA ameliorates sepsis-induced myocardial injury via promoting macrophage M2 polarization by interacting with DUSP1

L Cheng, D Liu, S Gao - Regenerative Therapy, 2024 - Elsevier

Background The morbidity and mortality of sepsis are increasing year by year. Statistically,
40–50% of patients with sepsis have concomitant myocardial injury, and its mortality rate is …

GCN5L1 regulates glucose and ketone body metabolism during cardiac ischemia-reperfusion injury

P Bugga, M Stoner, J Manning, B Mushala, N Bhattarai… - bioRxiv, 2024 - biorxiv.org

Ischemic heart diseases are the leading cause of death among cardiovascular diseases.
Reperfusion of the ischemic myocardium is the only way to treat IHD. However, reperfusion …

Identification of novel prognostic targets in acute kidney injury using bioinformatics and next generation sequencing data analysis

BM Vastrad, CM Vastrad - bioRxiv, 2024 - biorxiv.org

Acute kidney injury (AKI) is a type of renal disease occurs frequently in hospitalized patients,
which may cause abnormal renal function and structure with increase in serum creatinine …