Background The degree of efficacy, safety, quality, and certainty of meta-analytic evidence of
biological non-pharmacological treatments in mental disorders is unclear. Methods We …

Background. Fasting interventions have shown effectiveness in alleviating stress, anxiety
and depressive symptoms. However, no quantitative analysis has been carried out thus far …

Circadian rhythms have evolved in almost all organisms enabling them to anticipate
alternating changes in the environment. As a consequence, the circadian clock controls a …

Sleep loss pervasively affects the human brain at multiple levels. Age-related changes in
several sleep characteristics indicate that reduced sleep quality is a frequent characteristic …

Sleep deprivation, alone or in combination with pharmacological treatment and as part of a
chronotherapy package, is of potential use for people with major depressive episodes …

Background Sleep deprivation (SD) has been suggested to have a rapid antidepressant
effect. There is substantial evidence that neuroinflammation and neuroplasticity play critical …

Ample sleep is an important basis for maintaining health, however with the pace of life
accelerating in modern society, more people are using sacrificial sleep to cope with these …

Bright light therapy is an effective treatment option for seasonal and non-seasonal affective
disorders. However up to now, no study has investigated effects of dynamic bedroom …

Introduction Sleep deprivation and electroconvulsive therapy (ECT) effectively ameliorate
symptoms in major depressive disorder (MDD). In rodents, both are associated with an …

Backgrounds Depression is the most common mental disorder in the world. Sleep
deprivation (SD) is a well-known antidepressant. Several recombination protocols (including …