Granulocyte-macrophage colony-stimulating factor (GM-CSF) is a cytokine that drives the
generation of myeloid cell subsets including neutrophils, monocytes, macrophages, and …

Eosinophils play a homeostatic role in the body's immune responses. These cells are
involved in combating some parasitic, bacterial, and viral infections and certain cancers and …

Eosinophils are evolutionarily conserved, pleotropic cells that display key effector functions
in allergic diseases, such as asthma. Nonetheless, eosinophils infiltrate multiple tumours …

Eosinophils are important effector cells and therapeutic targets in allergic diseases.
Emerging data indicate that eosinophils infiltrate a variety of solid tumor types and have …

Granulocyte–macrophage colony-stimulating factor (GM-CSF) has many more functions
than its original in vitro identification as an inducer of granulocyte and macrophage …

Metastasis constitutes the primary cause of cancer-related deaths, with the lung being a
commonly affected organ. We found that activation of lung-resident group 2 innate lymphoid …

Cytokine signaling represents one of the cornerstones of the immune system, mediating the
complex responses required to facilitate appropriate immune cell development and function …

Chronic rhinosinusitis with nasal polyps (CRSwNP) is generally associated with eosinophilic
tissue infiltration linked to type 2 inflammation and characterized by elevated levels of …

abstract Biologics have been a key component of severe asthma treatment, and there are
currently biologics available that target IgE, IL-5, IL-4/IL-13, and TSLP. Randomized …

abstract IL-5 is the most potent activator of eosinophils and is produced by Th2 cells and
ILC2s. A role for IL-5 in eosinophil extracellular trap cell death, ie, a proinflammatory cell …