Neural circuit tracing methods that take advantage of viral vectors and transgenic mice
provide opportunities to gain insight into functional connectivity. Here we describe several …

One of the important problems in the treatment of addiction is the vulnerability of previously
addicted individuals to relapse to drug use months or even years after abstinence …

Exaggerated impulsivity and attentional impairments are hallmarks of certain disorders of
behavioural control such as attention-deficit/hyperactivity disorder (ADHD), schizophrenia …

The combination of chemogenetics targeting specific brain cell populations with invivo
imaging techniques provides scientists with a powerful new tool to study functional neural …

Pain Induced Adaptations in Ventral Tegmental Area Dopamine Neurons to Drive Anhedonia-like
Behaviour Page 1 Ottawa-Carleton Journal of Neuroethology June 1st, 2023 OCJN (2023) Vol. 1 …

Millions of people experience at least one episode of major depressive disorder in their
lifetime, and diagnostic rates are increasing. Depression is a heterogeneous and complex …

Age-related hearing loss (ARHL) or presbycusis has grown to be a prevalent problem
among the increasing aging population over the past century. Efficacy of hearing aids …

Objective More than one third of patients with Temporal Lobe Epilepsy (TLE) continue to
have seizures despite treatment with anti-epileptic drugs and many experience severe drug …

The serotonergic system is important in modulating a range of emotional behaviors, and
disturbances of this system are implicated in psychiatric conditions such as post-traumatic …

The persistence of negative affect in pain leads to co-morbid symptoms, such as anhedonia
and depression, representing a major health issue in the US. However, the neuronal …