Recent advances in biosensors for diagnosis and detection of sepsis: A comprehensive review

S Kumar, S Tripathy, A Jyoti, SG Singh - Biosensors and Bioelectronics, 2019 - Elsevier
Sepsis is one of the leading causes of mortality among critically ill patients globally.
According to WHO report 2018, it is estimated to affect beyond 30 million people worldwide …

Sepsis biomarkers

M Prucha, G Bellingan, R Zazula - Clinica chimica acta, 2015 - Elsevier
Sepsis is the most frequent cause of death in non-coronary intensive care units (ICUs). In the
past 10 years, progress has been made in the early identification of septic patients and in …

Heparin‐binding protein: a key player in the pathophysiology of organ dysfunction in sepsis

J Fisher, A Linder - Journal of Internal Medicine, 2017 - Wiley Online Library
Infectious diseases remain a major health problem, and sepsis and other severe infectious
diseases are common causes of morbidity and mortality. There is a need for clinical and …

Biomarkers for sepsis: what is and what might be?

BM Biron, A Ayala, JL Lomas-Neira - Biomarker insights, 2015 - journals.sagepub.com
Every year numerous individuals develop the morbid condition of sepsis. Therefore, novel
biomarkers that might better inform clinicians treating such patients are sorely needed …

Neutrophil CD64: a diagnostic marker for infection and sepsis

JJML Hoffmann - Clinical chemistry and laboratory medicine, 2009 - degruyter.com
Neutrophilic granulocytes express Fcγ receptor (FcγR)[cluster of differentiation 64 (CD64)
antigen] only when they are activated. Neutrophil CD64, demonstrated using flow cytometry …

Diagnostic value of neutrophil CD64, procalcitonin, and interleukin-6 in sepsis: a meta-analysis

S Cong, T Ma, X Di, C Tian, M Zhao, K Wang - BMC infectious diseases, 2021 - Springer
Background The aim of the study was to conduct a meta-analysis to evaluate the accuracy of
neutrophil CD64, procalcitonin (PCT), and interleukin-6 (IL-6) as markers for the diagnosis of …

Prognostic value of phagocytic activity of neutrophils and monocytes in sepsis. Correlation to CD64 and CD14 antigen expression

DD Danikas, M Karakantza… - Clinical & …, 2008 - academic.oup.com
The role of the phagocytic function of monocytes and neutrophils in sepsis has been poorly
investigated. The present study evaluated the impact of the phagocytic activity of neutrophils …

Hematologic profile of sepsis in neonates: neutrophil CD64 as a diagnostic marker

V Bhandari, C Wang, C Rinder, H Rinder - Pediatrics, 2008 - publications.aap.org
OBJECTIVE. The goal was to determine the utility of neutrophil CD64 as a diagnostic marker
for sepsis in neonates. METHODS. A prospective study that enrolled consecutive infants with …

Neutrophil CD64 expression as marker of bacterial infection: a systematic review and meta-analysis

J Cid, R Aguinaco, R Sánchez, G García-Pardo… - Journal of Infection, 2010 - Elsevier
OBJECTIVE: We performed a systematic review and meta-analysis of studies to evaluate the
diagnostic accuracy of expression of CD64 on polymorphonuclear neutrophils (PMN) as a …

Neutrophil CD64 expression as a diagnostic marker for sepsis in adult patients: a meta-analysis

X Wang, ZY Li, L Zeng, AQ Zhang, W Pan, W Gu… - Critical Care, 2015 - Springer
Abstract Introduction Neutrophil CD64 (nCD64) expression appears to be a promising
marker of bacterial infections. The aim of this meta-analysis was to assess the accuracy of …