1, 25-Dihydroxvitamin D3 [1, 25 (OH) 2D3] is the hormonally active form of vitamin D. The
genomic mechanism of 1, 25 (OH) 2D3 action involves the direct binding of the 1, 25 (OH) …

Vitamin D is not really a vitamin but the precursor to the potent steroid hormone calcitriol,
which has widespread actions throughout the body. Calcitriol regulates numerous cellular …

Human skin pigmentation is the product of two clines produced by natural selection to adjust
levels of constitutive pigmentation to levels of UV radiation (UVR). One cline was generated …

There has been substantial enthusiasm recently regarding the potential role of vitamin D in
the primary and secondary prevention of cancer. Laboratory studies demonstrate a range of …

Vitamin D is a pleiotropic secosteroid hormone important for health and disease prevention.
The actions of vitamin D are mediated by the vitamin D receptor that binds the active form of …

Vitamin D is synthesized predominantly in the liver and functions as an important
secosteroid hormone with pleiotropic effects. While its key regulatory role in calcium and …

Background: Vitamin D has been linked with improved cancer outcome. This systematic
review and meta-analysis investigates the relationship between cancer outcomes and both …

In many cells throughout the body, vitamin D is converted into its active form calcitriol and
binds to the vitamin D receptor (VDR), which functions as a transcription factor to regulate …

Introduction Growing evidence documented the critical impacts of vitamin D (VD) in the
prognosis of COVID-19 patients. The functions of VD are dependent on the vitamin D …

Vitamin D plays important, pleiotropic role in the maintenance of global homeostasis. Its
influence goes far beyond the regulation of calcium and phosphorus balance, as diverse …