The medial frontal cortex and adjacent orbitofrontal cortex have been the focus of
investigations of decision-making, behavioral flexibility, and social behavior. We review …

Increasing evidence suggests that mental health and physical health are linked by neural
systems that jointly regulate somatic physiology and high-level cognition. Key systems …

A major shift is happening within neurophysiology: a population doctrine is drawing level
with the single-neuron doctrine that has long dominated the field. Population-level ideas …

Recent breakthroughs in artificial intelligence (AI) have enabled machines to plan in tasks
previously thought to be uniquely human. Meanwhile, the planning algorithms implemented …

During decision-making, neurons in the orbitofrontal cortex (OFC) sequentially represent the
value of each option in turn, but it is unclear how these dynamics are translated into a choice …

The outcome of a decision is often uncertain, and outcomes can vary over repeated
decisions. Whether decision outcomes should substantially affect behaviour and learning …

Decisions made by mammals and birds are often temporally extended. They require
planning and sampling of decision-relevant information. Our understanding of such decision …

We propose that the entirety of the prefrontal cortex (PFC) can be seen as fundamentally
premotor in nature. By this, we mean that the PFC consists of an action abstraction hierarchy …

Human reasoning depends on reusing pieces of information by putting them together in new
ways. However, very little is known about how compositional computation is implemented in …

Much of traditional neuroeconomics proceeds from the hypothesis that value is reified in the
brain, that is, that there are neurons or brain regions whose responses serve the discrete …