[HTML][HTML] Focus on negatively regulated NLRs in inflammation and cancer

J Wang, W He, C Li, Y Ma, M Liu, J Ye, L Sun… - International …, 2024 - Elsevier
Nucleotide-binding and oligomerization structural domain (NOD)-like receptors (NLRs) play
an important role in innate immunity as cytoplasmic pattern recognition receptors (PRRs) …

[HTML][HTML] P2X7 receptors from the perspective of NLRP3 inflammasome pathway in depression: Potential role of cannabidiol

E Akcay, H Karatas - Brain, Behavior, & Immunity-Health, 2024 - Elsevier
Many patients with depressive disorder do not respond to conventional antidepressant
treatment. There is an ongoing interest in investigating potential mechanisms of treatment …

Impact of cannabidiol on myocardial recovery in patients with acute myocarditis: Rationale & design of the ARCHER trial

DM McNamara, LT Cooper, Y Arbel… - ESC Heart …, 2024 - Wiley Online Library
Aims Acute myocarditis, although a rare disease, can be associated with sudden cardiac
death or the need for transplantation in both children and young adults. To date, there is no …

Protective Effects of Cannabidiol (CBD) against Qxidative Stress, but Not Excitotoxic-Related Neuronal Cell Damage—An In Vitro Study

D Jantas, M Leśkiewicz, M Regulska, M Procner… - Biomolecules, 2024 - mdpi.com
Cannabidiol (CBD) appears to possess some neuroprotective properties, but experimental
data are still inconsistent. Therefore, this in vitro study aimed to compare the effects of CBD …

Cannabidiol suppresses silica-induced pulmonary inflammation and fibrosis through regulating NLRP3/TGF-β1/Smad2/3 pathway

W Shao, J Zhang, Z Yao, P Zhao, B Li, W Tang… - International …, 2024 - Elsevier
Silica-induced pulmonary fibrosis is an irreversible and progressive lung disease with
limited treatments available. In this work, FDA-approved cannabidiol (CBD) was studied for …

Full‐spectrum cannabidiol reduces UVB damage through the inhibition of TGF‐β1 and the NLRP3 inflammasome

IM Urrutia‐Ortega, I Valencia… - Photochemistry and …, 2024 - Wiley Online Library
The thermodynamic characteristics, antioxidant potential, and photoprotective benefits of full‐
spectrum cannabidiol (FS‐CBD) against UVB‐induced cellular death were examined in this …