Role of JAK/STAT in interstitial lung diseases; molecular and cellular mechanisms
P Montero, J Milara, I Roger, J Cortijo - International journal of molecular …, 2021 - mdpi.com
Interstitial lung diseases (ILDs) comprise different fibrotic lung disorders characterized by
cellular proliferation, interstitial inflammation, and fibrosis. The JAK/STAT molecular pathway …
cellular proliferation, interstitial inflammation, and fibrosis. The JAK/STAT molecular pathway …
Computer-aided detection in chest radiography based on artificial intelligence: a survey
C Qin, D Yao, Y Shi, Z Song - Biomedical engineering online, 2018 - Springer
As the most common examination tool in medical practice, chest radiography has important
clinical value in the diagnosis of disease. Thus, the automatic detection of chest disease …
clinical value in the diagnosis of disease. Thus, the automatic detection of chest disease …
Mechanisms of progressive fibrosis in connective tissue disease (CTD)-associated interstitial lung diseases (ILDs)
P Spagnolo, O Distler, CJ Ryerson… - Annals of the …, 2021 - ard.bmj.com
Interstitial lung diseases (ILDs), which can arise from a broad spectrum of distinct
aetiologies, can manifest as a pulmonary complication of an underlying autoimmune and …
aetiologies, can manifest as a pulmonary complication of an underlying autoimmune and …
Riociguat for idiopathic interstitial pneumonia-associated pulmonary hypertension (RISE-IIP): a randomised, placebo-controlled phase 2b study
Background Idiopathic interstitial pneumonias are often complicated by pulmonary
hypertension, increasing morbidity and mortality. There are no approved treatments for …
hypertension, increasing morbidity and mortality. There are no approved treatments for …
Trends in prevalence and incidence of chronic respiratory diseases from 1990 to 2017
M Xie, X Liu, X Cao, M Guo, X Li - Respiratory research, 2020 - Springer
Abstract Background Chronic respiratory diseases (CRDs) are leading causes of morbidity
worldwide. However, the spatial and temporal trends in prevalence and incidence of CRDs …
worldwide. However, the spatial and temporal trends in prevalence and incidence of CRDs …
The roles of exosomal miRNAs and lncRNAs in lung diseases
Y Li, Z Yin, J Fan, S Zhang, W Yang - Signal transduction and targeted …, 2019 - nature.com
An increasing number of studies have reported that exosomes released from various cells
can serve as mediators of information exchange between different cells. With further …
can serve as mediators of information exchange between different cells. With further …
Interstitial lung disease in primary Sjögren's syndrome
F Roca, S Dominique, J Schmidt, A Smail, P Duhaut… - Autoimmunity …, 2017 - Elsevier
Interstitial lung disease (ILD) has been reported in 3 to 11% of patients with primary
Sjögren's syndrome (pSS). The aims of this retrospective multicenter study were to: 1) …
Sjögren's syndrome (pSS). The aims of this retrospective multicenter study were to: 1) …
The smell of lung disease: a review of the current status of electronic nose technology
IG Van der Sar, N Wijbenga, G Nakshbandi, J Aerts… - Respiratory …, 2021 - Springer
There is a need for timely, accurate diagnosis, and personalised management in lung
diseases. Exhaled breath reflects inflammatory and metabolic processes in the human body …
diseases. Exhaled breath reflects inflammatory and metabolic processes in the human body …
Molecular and clinical features of EGFR-TKI-associated lung injury
T Ohmori, T Yamaoka, K Ando, S Kusumoto… - International Journal of …, 2021 - mdpi.com
The tyrosine kinase activity of epidermal growth factor receptors (EGFRs) plays critical roles
in cell proliferation, regeneration, tumorigenesis, and anticancer resistance. Non-small-cell …
in cell proliferation, regeneration, tumorigenesis, and anticancer resistance. Non-small-cell …
Circadian clock molecule REV-ERBα regulates lung fibrotic progression through collagen stabilization
Molecular clock REV-ERBα is central to regulating lung injuries, and decreased REV-ERBα
abundance mediates sensitivity to pro-fibrotic insults and exacerbates fibrotic progression. In …
abundance mediates sensitivity to pro-fibrotic insults and exacerbates fibrotic progression. In …