Photon counting CT: technical principles, clinical applications, and future prospects

Y Wu, Z Ye, J Chen, L Deng, B Song - Academic Radiology, 2023 - Elsevier
Photon-counting computed tomography (PCCT) is a new technique that utilizes photon-
counting detectors to convert individual X-ray photons directly into an electrical signal, which …

Pamrevlumab for the treatment of idiopathic pulmonary fibrosis

G Sgalla, C Franciosa, J Simonetti… - Expert Opinion on …, 2020 - Taylor & Francis
Introduction The two available therapies for idiopathic pulmonary fibrosis (IPF), pirfenidone
and nintedanib, slow down but do not halt IPF progression. As such, in the last few years …

Smoking and interstitial lung diseases

GA Margaritopoulos, E Vasarmidi… - European …, 2015 - Eur Respiratory Soc
For many years has been well known that smoking could cause lung damage. Chronic
obstructive pulmonary disease and lung cancer have been the two most common smoking …

[HTML][HTML] Gas6/TAM system: a key modulator of the interplay between inflammation and fibrosis

M Bellan, MG Cittone, S Tonello, C Rigamonti… - International journal of …, 2019 - mdpi.com
Fibrosis is the result of an overly abundant deposition of extracellular matrix (ECM) due to
the fact of repetitive tissue injuries and/or dysregulation of the repair process. Fibrogenesis …

[HTML][HTML] Collagen 1a1 expression by airway macrophages increases in fibrotic ILDs and is associated with FVC decline and increased mortality

E Tsitoura, A Trachalaki, E Vasarmidi… - Frontiers in …, 2021 - frontiersin.org
Within the Interstitial Lung Diseases (ILD), patients with idiopathic pulmonary fibrosis (IPF)
and a subset of those with non-IPF fibrotic ILD have a distinct clinical phenotype of …

[HTML][HTML] Involvement of the ACE2/Ang-(1–7)/MasR axis in pulmonary fibrosis: implications for COVID-19

T Morganstein, Z Haidar, J Trivlidis, I Azuelos… - International Journal of …, 2021 - mdpi.com
Pulmonary fibrosis is a chronic, fibrotic lung disease affecting 3 million people worldwide.
The ACE2/Ang-(1–7)/MasR axis is of interest in pulmonary fibrosis due to evidence of its anti …

[HTML][HTML] The association between idiopathic pulmonary fibrosis and obstructive sleep apnea: a systematic review and meta-analysis

FF Karuga, P Kaczmarski, B Szmyd… - Journal of Clinical …, 2022 - mdpi.com
The prevalence of obstructive sleep apnea (OSA) has greatly increased in recent years.
Recent data suggest that severe and moderate forms of OSA affect between 6 and 17% of …

Immune-related adverse events: pneumonitis

L Zhong, M Altan, VR Shannon, A Sheshadri - Immunotherapy, 2020 - Springer
Checkpoint inhibitors are part of the family of immunotherapies and are increasingly being
used in a wide variety of cancers. Immune-related adverse events pose a major challenge in …

[HTML][HTML] Patients with interstitial lung disease secondary to autoimmune diseases: how to recognize them?

D Sambataro, G Sambataro, F Pignataro… - Diagnostics, 2020 - mdpi.com
The diagnostic assessment of patients with Interstitial Lung Disease (ILD) can be
challenging due to the large number of possible causes. Moreover, the diagnostic approach …

Human antigen R promotes lung fibroblast differentiation to myofibroblasts and increases extracellular matrix production

F Al‐Habeeb, N Aloufi, H Traboulsi… - Journal of cellular …, 2021 - Wiley Online Library
Idiopathic pulmonary fibrosis (IPF) is a disease of progressive scarring caused by excessive
extracellular matrix (ECM) deposition and activation of α‐SMA‐expressing myofibroblasts …