We herein summarise the evidence concerning the impact of sperm DNA fragmentation in
various clinical infertility scenarios and the advances on sperm DNA fragmentation tests …

Sperm DNA integrity is crucial for fertilization and development of healthy offspring. The
spermatozoon undergoes extensive molecular remodeling of its nucleus during later phases …

The clinical effect of sperm DNA damage in assisted reproduction has been a controversial
topic during recent decades, leading to a variety of clinical practice recommendations. While …

BACKGROUND Infertility and pregnancy loss are longstanding problems. Successful
fertilization and high-quality embryos are prerequisites for an ongoing pregnancy. Studies …

One important reason for male infertility is oxidative stress and its destructive effects on
sperm structures and functions. The particular composition of the sperm membrane, rich in …

STUDY QUESTION What effects did treatment using hyaluronic acid (HA) binding/selection
prior to ICSI have on clinical outcomes in the Hyaluronic Acid Binding sperm Selection …

Background Sperm chromatin integrity is essential for normal embryo development and
pregnancy outcome. Sperm DNA fragmentation (SDF) testing constitutes a diagnostic tool to …

Based on the inconsistent literature published thus far involving infertile patients, whether
intracytoplasmic sperm injection (ICSI) allows overcoming total fertilization failure due to …

The spermatozoon is a highly specialized cell, whose main function is the transport of the
intact male genetic material into the oocyte. During its formation and transit throughout male …

Osteoarthritis (OA) has long been viewed as a degenerative disease of cartilage, but
accumulating evidence indicates that inflammation has a critical role in its pathogenesis. In …