International consensus statement on allergy and rhinology: Allergic rhinitis–2023

SK Wise, C Damask, LT Roland, C Ebert… - International forum of …, 2023 - Wiley Online Library
Background In the 5 years that have passed since the publication of the 2018 International
Consensus Statement on Allergy and Rhinology: Allergic Rhinitis (ICAR‐Allergic Rhinitis …

Lupus nephritis: new progress in diagnosis and treatment

C Yu, P Li, X Dang, X Zhang, Y Mao, X Chen - Journal of autoimmunity, 2022 - Elsevier
Systemic lupus erythematosus (SLE) is a chronic multifactorial autoimmune disease that
affects many organs, including the kidney. Lupus nephritis (LN) is a common manifestation …

Anifrolumab efficacy and safety by type I interferon gene signature and clinical subgroups in patients with SLE: post hoc analysis of pooled data from two phase III …

EM Vital, JT Merrill, EF Morand, RA Furie… - Annals of the …, 2022 - ard.bmj.com
Objectives To characterise the efficacy and safety of anifrolumab in patients with systemic
lupus erythematosus (SLE) according to interferon gene signature (IFNGS), demographic …

Pathogenic cellular and molecular mediators in lupus nephritis

C Mohan, T Zhang, C Putterman - Nature Reviews Nephrology, 2023 - nature.com
Kidney involvement in patients with systemic lupus erythematosus—lupus nephritis (LN)—is
one of the most important and common clinical manifestations of this disease and occurs in …

[HTML][HTML] Advances in the pathogenesis and treatment of systemic lupus erythematosus

D Accapezzato, R Caccavale, MP Paroli… - International journal of …, 2023 - mdpi.com
Systemic lupus erythematosus (SLE) is a genetically predisposed, female-predominant
disease, characterized by multiple organ damage, that in its most severe forms can be life …

[HTML][HTML] The JAK-STAT pathway: from structural biology to cytokine engineering

Y Lv, J Qi, JJ Babon, L Cao, G Fan, J Lang… - … and Targeted Therapy, 2024 - nature.com
The Janus kinase-signal transducer and activator of transcription (JAK-STAT) pathway
serves as a paradigm for signal transduction from the extracellular environment to the …

[HTML][HTML] Belimumab or anifrolumab for systemic lupus erythematosus? A risk-benefit assessment

KA Kirou, M DallEra, C Aranow, HJ Anders - Frontiers in Immunology, 2022 - frontiersin.org
Treatment of systemic lupus erythematosus (SLE) currently employs agents with relatively
unselective immunosuppressive properties. However, two target-specific biological drugs …

Concordance and discordance in SLE clinical trial outcome measures: analysis of three anifrolumab phase 2/3 trials

IN Bruce, RA Furie, EF Morand, S Manzi… - Annals of the …, 2022 - ard.bmj.com
Objectives In the anifrolumab systemic lupus erythematosus (SLE) trial programme, there
was one trial (TULIP-1) in which BILAG-based Composite Lupus Assessment (BICLA) …

Cell-free DNA derived from neutrophils triggers type 1 interferon signature in neuromyelitis optica spectrum disorder

H Murata, M Kinoshita, Y Yasumizu… - Neurology …, 2022 - AAN Enterprises
Background and Objectives Recently accumulating evidence suggests the pivotal role of
type 1 interferon (IFN-1) signature in the pathogenesis of neuromyelitis optica spectrum …

Safety and efficacy of anifrolumab therapy in systemic lupus erythematosus in real-world clinical practice: LOOPS registry

Y Miyazaki, M Funada, S Nakayamada… - …, 2024 - academic.oup.com
Objective To determine the safety and efficacy of anifrolumab in patients with systemic lupus
erythematosus (SLE) classified based on the Lupus Low Disease Activity State (LLDAS) in …