Helicobacter pylori: an up-to-date overview on the virulence and pathogenesis mechanisms

HC Sharndama, IE Mba - Brazilian Journal of Microbiology, 2022 - Springer
Helicobacter pylori is an organism associated with ulcer disease and gastric cancer. The
latter is one of the most prevalent malignancies and currently the fourth major cause of …

Helicobacter pylori in Human Stomach: The Inconsistencies in Clinical Outcomes and the Probable Causes

SM Alexander, RJ Retnakumar, D Chouhan… - Frontiers in …, 2021 - frontiersin.org
Pathogenic potentials of the gastric pathogen, Helicobacter pylori, have been proposed,
evaluated, and confirmed by many laboratories for nearly 4 decades since its serendipitous …

A Pseudomonas aeruginosa small RNA regulates chronic and acute infection

P Cao, D Fleming, DA Moustafa, SK Dolan… - Nature, 2023 - nature.com
The ability to switch between different lifestyles allows bacterial pathogens to thrive in
diverse ecological niches,. However, a molecular understanding of their lifestyle changes …

Helicobacter pylori in the post-antibiotics era: from virulence factors to new drug targets and therapeutic agents

OM Al-Fakhrany, E Elekhnawy - Archives of Microbiology, 2023 - Springer
Helicobacter pylori is considered one of the most prevalent human pathogenic microbes
globally. It is the main cause of a number of gastrointestinal ailments, including peptic and …

Diversity and versatility in small RNA-mediated regulation in bacterial pathogens

B Felden, Y Augagneur - Frontiers in Microbiology, 2021 - frontiersin.org
Bacterial gene expression is under the control of a large set of molecules acting at multiple
levels. In addition to the transcription factors (TFs) already known to be involved in global …

Interference of flagellar rotation up-regulates the expression of small RNA contributing to Bordetella pertussis infection

Y Hiramatsu, T Nishida, DK Nugraha, M Osada-Oka… - Science …, 2022 - science.org
Bacterial small RNAs (sRNAs) posttranscriptionally regulate gene expressions involved in
various biological processes, including pathogenicity. Our previous study identified sRNAs …

[HTML][HTML] Influence of Helicobacter pylori oncoprotein CagA in gastric cancer: A critical-reflective analysis

FF de Melo, HS Marques, SLR Pinheiro… - World journal of …, 2022 - ncbi.nlm.nih.gov
Gastric cancer is the fifth most common malignancy and third leading cancer-related cause
of death worldwide. Helicobacter pylori is a Gram-negative bacterium that inhabits the …

Targeting of regulators as a promising approach in the search for novel antimicrobial agents

D Roncarati, V Scarlato, A Vannini - Microorganisms, 2022 - mdpi.com
Since the discovery of penicillin in the first half of the last century, antibiotics have become
the pillars of modern medicine for fighting bacterial infections. However, pathogens resistant …

[HTML][HTML] Gastrointestinal tract microbiome-derived pro-inflammatory neurotoxins in Alzheimer's disease

Y Zhao, V Jaber, WJ Lukiw - Journal of aging science, 2021 - ncbi.nlm.nih.gov
The microbiome contained within the human gastrointestinal (GI)-tract constitutes a highly
complex, dynamic and interactive internal prokaryotic ecosystem that possesses a …

Small RNA mediated gradual control of lipopolysaccharide biosynthesis affects antibiotic resistance in Helicobacter pylori

SR Pernitzsch, M Alzheimer, BU Bremer… - Nature …, 2021 - nature.com
The small, regulatory RNA RepG (Re gulator of p olymeric G-repeats) regulates the
expression of the chemotaxis receptor TlpB in Helicobacter pylori by targeting a variable G …