It is important that the medical profession play a significant role in critically evaluating the
use of diagnostic procedures and therapies as they are introduced and tested in the …

Late-breaking clinical trials presented at the 2005, 2006, and 2007 annual scientific
meetings of the ACCF, AHA, and European Society of Cardiology, as well as selected other …

2013 ACCF/AHA Guideline for the Management of Heart Failure: A Report of the American
College of Cardiology Foundation/American Heart Association Task Force on Practice …

The recommendations listed in this document are, whenever possible, evidence based. An
extensive evidence review was conducted through October 2011 and includes selected …

Patient health status includes 3 components: symptom burden, functional status, and health-
related quality of life (HRQL; Figure). 7 Symptom burden includes the types and frequency of …

In recent years quality of life instruments have been featured as primary outcomes in many
randomized trials. One of the challenges facing the investigator using such measures is …

Heart failure (HF) is a major and growing public health problem in the United States.
Approximately 5 million patients in this country have HF, and over 550 000 patients are …

OBJECTIVES To create a valid, sensitive, disease-specific health status measure for
patients with congestive heart failure (CHF). BACKGROUND Quantifying health status is …

Because physicians have traditionally considered heart failure to be a hemodynamic
disorder, they have described the syndrome of heart failure using hemodynamic concepts …

▪ The extent to which a clinician should believe and act on the results of subgroup analyses
of data from randomized trials or meta-analyses is controversial. Guidelines are provided in …