The neurovascular unit (NVU) is composed of vascular cells, glial cells, and neurons. As a
fundamental functional module in the central nervous system, the NVU maintains …

The receptor for advanced glycation end products (RAGE) is a non-specific multi-ligand
pattern recognition receptor capable of binding to a range of structurally diverse ligands …

As a critical molecule in the onset and sustainment of inflammatory response, the receptor
for advanced glycation end products (RAGE) has a variety of ligands, such as advanced …

Nonenzymatic reactions of reducing sugars with primary amino groups of amino acids,
proteins, and nucleic acids, followed by oxidative degradations would lead to the formation …

Diabetes and its complications, Alzheimer's disease (AD), and Parkinson's disease (PD) are
increasing gradually, reflecting a global threat vis‐à‐vis expressing the essentiality of a …

Osteoarthritis (OA) is progressive disease characterised by cartilage degradation,
subchondral bone remodelling and inflammation of the synovium. The disease is associated …

Atherosclerosis is a complex disease, and there are many factors that influence its
development and the course of the disease. A deep understanding of the pathological …

The S100B is a member of the S100 family of “E” helix–loop-“F” helix structure (EF) hand
calcium-binding proteins expressed in diverse glial, selected neuronal, and various …

Neutrophils are the most abundant immune cell in the circulation of human and act as
gatekeepers to discard foreign elements that have entered the body. They are essential in …

Advanced glycation end products (AGEs) are a class of compounds formed by
nonenzymatic interactions between reducing sugars and proteins, lipids, or nucleic acids …