Technological innovation has helped the zebrafish embryo gain ground as a disease model
and an assay system for drug screening. Here, we review the use of zebrafish embryos and …

Testing of compounds for neurotoxicity has become increasingly important in recent years. It
has been shown that neurological disorders like autism may be related to chemical …

This study investigated the direct and indirect toxic effects of microplastics and nanoplastics
toward zebrafish (Danio rerio) larvae locomotor activity. Results showed that microplastics …

One of the current main challenges faced by the scientific community is concerning the fate
and toxicity of plastics, due to both the well-known threats made by larger plastic items …

Background In the drug discovery pipeline, safety pharmacology is a major issue. The
zebrafish has been proposed as a model that can bridge the gap in this field between cell …

Environmental pollution caused by pharmaceuticals has been recognized as a major threat
to the aquatic ecosystems. Carbamazepine, as the widely prescribed antiepileptic drug, has …

Zebrafish embryos and early larvae are becoming increasingly important as models in
biomedical research because of their low cost, high throughput and potential as a …

Wild-type (WT) zebrafish are commonly used in behavioral tests, but the term WT is not a
precise description, and corresponds to many different strains (eg, AB, TU, WIK, and others) …

A critical window (sensitive period) represents a period during development when an
organism's phenotype is responsive to intrinsic or extrinsic (environmental) factors. Such …

The zebrafish is a powerful whole animal model which is complementary to in vitro and
mammalian models. It has been shown to be applicable to the high-throughput behavioral …