Gabapentin and pregabalin in bipolar disorder, anxiety states, and insomnia: Systematic review, meta-analysis, and rationale

JSW Hong, LZ Atkinson, N Al-Juffali, A Awad… - Molecular …, 2022 - nature.com
The gabapentinoids, gabapentin, and pregabalin, target the α2δ subunits of voltage-gated
calcium channels. Initially licensed for pain and seizures, they have become widely …

Pharmacological therapy for post-traumatic stress disorder: a systematic review and meta-analysis of monotherapy, augmentation and head-to-head approaches

MD Hoskins, J Bridges, R Sinnerton… - European Journal of …, 2021 - Taylor & Francis
Background: Pharmacological approaches are widely used for post-traumatic stress
disorder (PTSD) despite uncertainty over efficacy. Objectives: To determine the efficacy of all …

Emerging drugs for the treatment of anxiety

JW Murrough, S Yaqubi, S Sayed… - Expert opinion on …, 2015 - Taylor & Francis
Introduction: Anxiety disorders are among the most prevalent and disabling psychiatric
disorders in the United States and worldwide. Basic research has provided critical insights …

Pharmacological strategies for post-traumatic stress disorder (PTSD): From animal to clinical studies

A Gasparyan, D Navarro, F Navarrete… - Neuropharmacology, 2022 - Elsevier
Post-traumatic stress disorder (PTSD) is a disabling psychiatric condition with a critical
familiar, personal, and social impact. Patients diagnosed with PTSD show various …

Treatment-refractory posttraumatic stress disorder (TRPTSD): a review and framework for the future

RJ Koek, HN Schwartz, S Scully, JP Langevin… - Progress in Neuro …, 2016 - Elsevier
Post-traumatic stress disorder (PTSD) is a serious psychiatric consequence of trauma that
occurs in a proportion of individuals exposed to life-threatening events. Trauma-focused …

Comparative efficacy and acceptability of pharmaceutical management for adults with post-traumatic stress disorder: a systematic review and meta-analysis

ZD Huang, YF Zhao, S Li, HY Gu, LL Lin… - Frontiers in …, 2020 - frontiersin.org
The current clinical guidelines on post-traumatic stress disorder (PTSD) recommend
selective serotonin reuptake inhibitors (SSRIs) and serotonin and norepinephrine reuptake …

A single injection of pregabalin induces short-and long-term beneficial effects on fear memory and anxiety-like behavior in rats with experimental type-1 diabetes …

AHB de Lima Silva, DR Radulski, GS Pereira… - Metabolic Brain …, 2022 - Springer
Abstract Anxiety Disorders and Posttraumatic Stress Disorders (PTSD) associated with type-
1 diabetes mellitus (T1DM) are increasingly common comorbidities and the treatment is …

[HTML][HTML] Pharmacotherapy for co-occurring alcohol use disorder and post-traumatic stress disorder: targeting the opioidergic, noradrenergic, serotonergic, and …

TL Verplaetse, SA McKee, IL Petrakis - Alcohol research: current …, 2018 - ncbi.nlm.nih.gov
Alcohol use disorder (AUD) and post-traumatic stress disorder (PTSD) are highly comorbid,
and treatment outcomes are worse in individuals with both disorders. Several …

[HTML][HTML] Anticonvulsant medication use in veterans with posttraumatic stress disorder

B Shiner, CL Westgate, NC Bernardy… - The Journal of clinical …, 2017 - ncbi.nlm.nih.gov
Objective: Anticonvulsants have been studied for many indications, including posttraumatic
stress disorder (PTSD). The limited efficacy research on anticonvulsants for PTSD is mixed …

Effect of rivastigmine augmentation in treatment of male patients with combat-related chronic posttraumatic stress disorder: a randomized controlled trial

AR Ardani, G Hosseini, MRF Bordbar… - Journal of Clinical …, 2017 - journals.lww.com
Background Posttraumatic stress disorder (PTSD) is one of the chronic and disabling
psychiatric disorders, particularly in combat veterans. In a case series, rivastigmine was …