Increasing evidence suggests that depression is accompanied by dysregulation of
neuroimmune system. Sulforaphane (SFN) is a natural compound with antioxidative, anti …

Panaxynol (PAL, also called falcarinol) is widely found in plants of the Umbelliferae family,
among which carrots are rich in PAL, so it is proved to be edible. PAL has neuroprotective …

Abstract Introduction Hyperactivity of the Hypothalamic-Pituitary-Adrenal (HPA) axis and
high cortisol levels have been widely reported in patients with mood disorders but previous …

Dehydroepiandrosterone (DHEA) and its sulfate ester, DHEAS, are the most abundant
steroid hormones in the humans. However, their physiological significance, their …

Peripheral inflammation induced by lipopolysaccharide (LPS) causes behavioural changes
indicative for depression. The possible mechanisms involve the interference with …

Tributyltin chloride (TBT) is an environmental contaminant that is used as a biocide in
antifouling paints. TBT has been shown to induce endocrine-disrupting effects. However …

Major depressive disorder (MDD) is a heterogeneous clinical syndrome involving distinct
pathological processes. Core features of MDD include anhedonia, reduced motivation …

Depression and pain are two of the most debilitating disorders worldwide and have an
estimated cooccurrence of up to 80%. Comorbidity of these disorders is more difficult to treat …

Aims Asthma is an airway inflammatory disease that is affected by neurological and
psychological factors. The aim of present review is to investigating the relationship between …

Stress activates the nuclear translocation of glucocorticoid receptors (GR) to trigger gene
expression. Abnormal GR levels can alter the stress responses in animals and therapeutic …