Daily treatment with the dual orexin receptor antagonist DORA-12 during oxycodone abstinence decreases oxycodone conditioned reinstatement
JM Illenberger, FJ Flores-Ramirez, G Pascasio… - …, 2023 - Elsevier
Chronic opioid use disturbs circadian rhythm and sleep, encouraging opioid use and
relapse. The orexin (OX) system is recruited by opioids and regulates physiological …
relapse. The orexin (OX) system is recruited by opioids and regulates physiological …
[HTML][HTML] Orexinergic Receptor Antagonists as a New Therapeutic Target to Overcome Limitations of Current Pharmacological Treatment of Insomnia Disorder
C Álamo, JS Ruiz, CZ Arnáez - Actas Españolas de Psiquiatría, 2024 - ncbi.nlm.nih.gov
Insomnia disorder is a common condition that is considered a risk factor for multiple physical
and mental disorders, contributing to reduced quality of life and increased healthcare …
and mental disorders, contributing to reduced quality of life and increased healthcare …
The potential use of daridorexant in eating disorders: beyond the treatment of insomnia?
A Caldiroli, LM Affaticati, E Capuzzi… - International Clinical …, 2024 - journals.lww.com
A strong interplay exists between sleep and dietary habits, and sleep disturbances have
been repeatedly documented in individuals with eating disorders (EDs). The orexin system …
been repeatedly documented in individuals with eating disorders (EDs). The orexin system …