Background Combining biologics and small molecules could potentially overcome the
plateau of drug efficacy in inflammatory bowel disease (IBD). We conducted a systematic …

Background Standard random-effects meta-analysis methods perform poorly when applied
to few studies only. Such settings however are commonly encountered in practice. It is …

Background To review and meta-analyse the evidence about the prevalence of barriers to
evidence-based practice (EBP) reported in physiotherapy. Methods Two independent …

Background: Antiplatelet agents are used to prevent cardiovascular events; however,
treatment effects may differ in persons with chronic kidney disease (CKD) because …

Background As the prevalence of hepatitis steatosis (HS) increases, the prevalence of HS
among those with chronic hepatitis B (CHB) may also be increasing but data on the effect of …

Background A fundamental aspect of epidemiological studies concerns the estimation of
factor-outcome associations to identify risk factors, prognostic factors and potential causal …

Background: Large cohort studies provide conflicting evidence regarding the potential for
oral macrolide antibiotics to increase the risk of serious cardiac events. Objectives: This …

Gastric cancer is the third leading cause of cancer-related mortality and the fifth most
common cancer globally. An estimated 1 million new cases and 750,000 related deaths are …

We aimed to consolidate all available data on worldwide third molar agenesis frequencies,
with a particular emphasis on exploring the factors leading authors to find contradictory …

Objective Our aim was to assess the safety of cyclooxygenase-2 (COX-2) inhibitors in the
management of osteoarthritis (OA) in a systematic review and meta-analysis of randomized …