The roles of androgens in humans: biology, metabolic regulation and health

M Alemany - International journal of molecular sciences, 2022 - mdpi.com
Androgens are an important and diverse group of steroid hormone molecular species. They
play varied functional roles, such as the control of metabolic energy fate and partition, the …

An overview of FSH-FSHR biology and explaining the existing conundrums

D Bhartiya, H Patel - Journal of Ovarian Research, 2021 - Springer
FSH was first identified in 1930 and is central to mammalian reproduction. It is indeed
intriguing that despite being researched upon for about 90 years, there is still so much more …

Actions and roles of FSH in germinative cells

K Recchia, AS Jorge, LVF Pessôa, RC Botigelli… - International Journal of …, 2021 - mdpi.com
Follicle stimulating hormone (FSH) is produced by the pituitary gland in a coordinated
hypothalamic–pituitary–gonadal (HPG) axis event, plays important roles in reproduction and …

[HTML][HTML] Signatures of selection in Nelore cattle revealed by whole-genome sequencing data

AM Maiorano, DF Cardoso, R Carvalheiro, GAF Júnior… - Genomics, 2022 - Elsevier
Nelore cattle breed was farmed worldwide due to its economic importance in the beef
market and adaptation to the tropics. In Brazil, purebred Nelore animals (PO) receive a …

Comprehensive analysis of differences in N6‐methyladenosine RNA methylomes in the rat adenohypophysis after GnRH treatment

HQ Wang, JB Zhang, Y Zheng, WD Zhang… - The FASEB …, 2022 - Wiley Online Library
N6‐methyladenosine is considered to be the most common and abundant internal chemical
modification among the more than 150 identified chemical RNA modifications. It is involved …

GnRH-driven FTO-mediated RNA m6A modification promotes gonadotropin synthesis and secretion

HQ Wang, YR Ma, YX Zhang, FH Wei, Y Zheng, ZH Ji… - BMC biology, 2024 - Springer
Background Gonadotropin precisely controls mammalian reproductive activities. Systematic
analysis of the mechanisms by which epigenetic modifications regulate the synthesis and …

[HTML][HTML] RNA-seq identifies differentially expressed genes involved in csal1 overexpression in granulosa cells of prehierarchical follicles in Chinese Dagu hens

H Zhu, Y Ding, J Zhu, L Zhao, Y Su, S Zhao - Poultry Science, 2023 - Elsevier
The transcription factor csal1 is an important molecule that plays a critical regulatory function
in ovarian follicle development, as confirmed by our previous data. However, the candidate …

[HTML][HTML] In silico insights into intra-and inter-species interactions of piscine gonadotropin hormones and receptor crosstalk

I Atre, N Mizrahi, K Hausken, B Levavi-Sivan - International Journal of …, 2024 - Elsevier
In mammals, the gonadotropins follicle-stimulating hormone (FSH) and luteinizing hormone
(LH) are macromolecules secreted during specific reproductive phases and display strict …

Single-Cell Transcriptional Profile Construction of Rat Pituitary Glands before and after Sexual Maturation and Identification of Novel Marker Spp1 in Gonadotropes

QH Huang, GK Zhao, HQ Wang, FH Wei… - International Journal of …, 2024 - mdpi.com
The mammalian pituitary gland drives highly conserved physiological processes such as
somatic cell growth, pubertal transformation, fertility, and metabolism by secreting a variety …

Study on the mechanism of scutellarin's protective effect against ZEA-induced mouse ovarian granulosa cells injury

Y Yi, Z Hao, P Sun, K Fan, W Yin, J Guo… - Food and Chemical …, 2022 - Elsevier
Zearalenone (ZEA), a mycotoxin produced by Fusarium, can cause reproductive disorders
by targeting ovarian granulosa cells (GCs). We previous showed that scutellarin (Scu) …