Evaluating the state of the art in missing data imputation for clinical data

Y Luo - Briefings in Bioinformatics, 2022 - academic.oup.com
Clinical data are increasingly being mined to derive new medical knowledge with a goal of
enabling greater diagnostic precision, better-personalized therapeutic regimens, improved …

Early intervention with 3BNC117 and romidepsin at antiretroviral treatment initiation in people with HIV-1: a phase 1b/2a, randomized trial

JD Gunst, MH Pahus, M Rosás-Umbert, IN Lu… - Nature medicine, 2022 - nature.com
Attempts to reduce the human immunodeficiency virus type 1 (HIV-1) reservoir and induce
antiretroviral therapy (ART)-free virologic control have largely been unsuccessful. In this …

A hybrid model for water quality prediction based on an artificial neural network, wavelet transform, and long short-term memory

J Wu, Z Wang - Water, 2022 - mdpi.com
Clean water is an indispensable essential resource on which humans and other living
beings depend. Therefore, the establishment of a water quality prediction model to predict …

[HTML][HTML] Handling missing data in clinical research

MW Heymans, JWR Twisk - Journal of clinical epidemiology, 2022 - Elsevier
Because missing data are present in almost every study, it is important to handle missing
data properly. First of all, the missing data mechanism should be considered. Missing data …

Methodological issues of the electronic health records' use in the context of epidemiological investigations, in light of missing data: a review of the recent literature

T Tsiampalis, D Panagiotakos - BMC medical research methodology, 2023 - Springer
Abstract Background Electronic health records (EHRs) are widely accepted to enhance the
health care quality, patient monitoring, and early prevention of various diseases, even when …

Association between triglyceride-glucose index and all-cause mortality in critically ill patients with ischemic stroke: analysis of the MIMIC-IV database

W Cai, J Xu, X Wu, Z Chen, L Zeng, X Song… - Cardiovascular …, 2023 - Springer
Abstract Background The triglyceride-glucose (TyG) index was significantly associated with
insulin resistance (IR). Several studies have validated the effect of TyG index on …

Safety and efficacy of venglustat in GBA1-associated Parkinson's disease: an international, multicentre, double-blind, randomised, placebo-controlled, phase 2 trial

N Giladi, RN Alcalay, G Cutter, T Gasser… - The Lancet …, 2023 - thelancet.com
Background Variants in the GBA1 gene, which encodes lysosomal acid glucocerebrosidase,
are among the most common genetic risk factors for Parkinson's disease and are associated …

Impact of BMI on outcomes in respiratory ECMO: an ELSO registry study

M Peetermans, I Guler, P Meersseman, A Wilmer… - Intensive care …, 2023 - Springer
Purpose The impact of body mass index (BMI) on outcomes in respiratory failure
necessitating extracorporeal membrane oxygenation (ECMO) has been poorly described …

Life's Essential 8 and risk of stroke: a prospective community-based study

S Wu, Z Wu, D Yu, S Chen, A Wang, A Wang, X Gao - Stroke, 2023 - Am Heart Assoc
BACKGROUND: Data are lacking regarding cardiovascular health (CVH) with Life's
Essential 8 approach and future stroke risk. We sought to elucidate whether the CVH score …

Stroke risk in women with atrial fibrillation

H Buhari, J Fang, L Han, PC Austin… - European Heart …, 2024 - academic.oup.com
Background and aims Female sex is associated with higher rates of stroke in atrial fibrillation
(AF) after adjustment for other CHA2DS2-VASc factors. This study aimed to describe sex …