[HTML][HTML] Cardiotoxicity of anticancer drugs: Molecular mechanisms and strategies for cardioprotection
MB Morelli, C Bongiovanni, S Da Pra… - Frontiers in …, 2022 - frontiersin.org
Chemotherapy and targeted therapies have significantly improved the prognosis of
oncology patients. However, these antineoplastic treatments may also induce adverse …
oncology patients. However, these antineoplastic treatments may also induce adverse …
[HTML][HTML] Exploring the promising potential of induced pluripotent stem cells in cancer research and therapy
M Chehelgerdi, F Behdarvand Dehkordi… - Molecular Cancer, 2023 - Springer
The advent of iPSCs has brought about a significant transformation in stem cell research,
opening up promising avenues for advancing cancer treatment. The formation of cancer is a …
opening up promising avenues for advancing cancer treatment. The formation of cancer is a …
Empagliflozin attenuates trastuzumab-induced cardiotoxicity through suppression of DNA damage and ferroptosis
J Min, L Wu, Y Liu, G Song, Q Deng, W Jin, W Yu… - Life Sciences, 2023 - Elsevier
Trastuzumab (TZM) is commonly used for target therapy in breast cancer patients with high
HER2 although the cardiotoxicity restricts its clinical usage. DNA damage and ferroptosis …
HER2 although the cardiotoxicity restricts its clinical usage. DNA damage and ferroptosis …
Nanotechnology Approaches for Prevention and Treatment of Chemotherapy‐Induced Neurotoxicity, Neuropathy, and Cardiomyopathy in Breast and Ovarian Cancer …
S Nevins, CD McLoughlin, A Oliveros, JB Stein… - Small, 2023 - Wiley Online Library
Nanotechnology has emerged as a promising approach for the targeted delivery of
therapeutic agents while improving their efficacy and safety. As a result, nanomaterial …
therapeutic agents while improving their efficacy and safety. As a result, nanomaterial …
Protective effect of curcumin, chrysin and thymoquinone injection on trastuzumab-induced cardiotoxicity via mitochondrial protection
LR Shirmard, M Shabani, AA Moghadam… - Cardiovascular …, 2022 - Springer
Mitochondrial dysfunction may lead to cardiomyocyte death in trastuzumab (TZM)-induced
cardiotoxicity. Accordingly, this study was designed to evaluate the mitochondrial protective …
cardiotoxicity. Accordingly, this study was designed to evaluate the mitochondrial protective …
[HTML][HTML] Anti-apoptotic and antioxidant mechanisms may underlie the abrogative potential of Ocimum gratissimum Linn. Leaf extract and fractions against trastuzumab …
Clinical use of trastuzumab (TZM), has been widely associated with increased incidence of
cardiotoxicity. Ocimum gratissimum Linn. is a household medicinal plant popularly used for …
cardiotoxicity. Ocimum gratissimum Linn. is a household medicinal plant popularly used for …
[HTML][HTML] Therapeutic options in neuro-oncology
M Afonso, MA Brito - International Journal of Molecular Sciences, 2022 - mdpi.com
One of the biggest challenges in neuro-oncology is understanding the complexity of central
nervous system tumors, such as gliomas, in order to develop suitable therapeutics …
nervous system tumors, such as gliomas, in order to develop suitable therapeutics …
[HTML][HTML] Cardioprotective agents for the primary prevention of trastuzumab-associated cardiotoxicity: a systematic review and meta-Analysis
K Goulas, D Farmakis, A Constantinidou… - Pharmaceuticals, 2023 - mdpi.com
There are significant considerations about the prevention of cardiotoxicity caused by
trastuzumab therapy in patients with breast cancer, leading to discontinuation. Recently …
trastuzumab therapy in patients with breast cancer, leading to discontinuation. Recently …
Women's cardiovascular health–the cardio-oncologic jigsaw
M Ray, LE Butel-Simoes, JM Lombard, IIC Nordman… - …, 2024 - Taylor & Francis
Improvements in cancer care have led to an exponential increase in cancer survival. This is
particularly the case for breast cancer, where 5-year survival in Australia exceeds 90 …
particularly the case for breast cancer, where 5-year survival in Australia exceeds 90 …
Monocyte-to-lymphocyte ratio as predictor of cancer therapy-related cardiotoxicity in patients with breast cancer: a pilot cohort study
F Pivatto Júnior, ÂBS Santos, EF Englert… - Breast Cancer Research …, 2023 - Springer
Background Elevated pre-treatment baseline inflammation has been associated with cancer
therapy-related cardiac dysfunction (CTRCD) in patients with breast cancer. Monocyte-to …
therapy-related cardiac dysfunction (CTRCD) in patients with breast cancer. Monocyte-to …