Pathogenesis, clinical features of asthma COPD overlap, and therapeutic modalities

S Dey, MS Eapen, C Chia… - … of Physiology-Lung …, 2022 - journals.physiology.org
Both asthma and COPD are heterogeneous diseases identified by characteristic symptoms
and functional abnormalities, with airway obstruction common in both diseases. Asthma …

Asthma-COPD overlap: what are the important questions?

C Leung, DD Sin - Chest, 2022 - Elsevier
Asthma-COPD overlap (ACO) is a heterogeneous condition that describes patients who
show persistent airflow limitation with clinical features that support both asthma and COPD …

[HTML][HTML] Genes and pathways regulating decline in lung function and airway remodeling in asthma

GY Hur, DH Broide - Allergy, asthma & immunology …, 2019 - synapse.koreamed.org
Asthma is a common disorder of the airways characterized by airway inflammation and by
decline in lung function and airway remodeling in a subset of asthmatics. Airway remodeling …

Differential role of mucus plugs in asthma: Effects of smoking and association with airway inflammation

A Oguma, K Shimizu, H Kimura, N Tanabe… - Allergology …, 2023 - jstage.jst.go.jp
Background: The physiological importance of mucus plugs in computed tomography (CT)
imaging is being increasingly recognized. However, whether airway inflammation and …

Differential airway remodeling changes were observed in patients with asthma COPD overlap compared to patients with asthma and COPD alone

S Dey, W Lu, HC Weber, S Young… - … of Physiology-Lung …, 2022 - journals.physiology.org
Management of patients with asthma COPD overlap (ACO) is clinically challenging due to
insufficient evidence of pathological changes in these patients. In this cross-sectional study …

[HTML][HTML] Associations of fractional exhaled nitric oxide with airway dimension and mucus plugs on ultra-high-resolution computed tomography in former smokers and …

Y Hayashi, N Tanabe, H Matsumoto, K Shimizu… - Allergology …, 2024 - Elsevier
Background Associations of fractional exhaled nitric oxide (FeNO) with airway wall
remodeling and mucus plugs remain to be explored in smokers and nonsmokers with …

Higher Prevalence and Severity of Eosinophilic Otitis Media in Patients with Asthma-COPD Overlap Compared with Asthma Alone

E Sato, Y Seo, E Tagaya, O Yagi… - … Archives of Allergy and …, 2023 - karger.com
Introduction: Eosinophilic otitis media (EOM) is well-known to frequently co-exist with adult-
onset asthma. Both diseases are similar type 2 inflammation and are considered to have a …

Assessment of airway remodeling using endobronchial ultrasound in asthma-COPD overlap

K Górka, I Gross-Sondej, J Górka… - Journal of Asthma …, 2021 - Taylor & Francis
Purpose The aim of this study was to evaluate the structural changes of the airways using
the endobronchial ultrasound (EBUS) in ACO patients compared to severe asthma and …

Imaging in Asthma-Chronic Obstructive Pulmonary Disease Overlap

S Svenningsen, M Kirby - Immunology and Allergy …, 2022 - immunology.theclinics.com
Asthma and chronic obstructive pulmonary disease (COPD) are both common chronic lung
diseases with considerable interpatient heterogeneity. The current definition of COPD is …

Genes and pathways regulating decline in lung function and airway remodeling in asthma.

HGY Hur GyuYoung, DH Broide - 2019 - cabidigitallibrary.org
Asthma is a common disorder of the airways characterized by airway inflammation and by
decline in lung function and airway remodeling in a subset of asthmatics. Airway remodeling …