Adenosine is a key metabolic and immune-checkpoint regulator implicated in the tumor
escape from the host immune system. Major gaps in knowledge that impede the …

Epithelial-mesenchymal transition (EMT) is reported to involve in the crosstalk between
tumor cells and tumor-associated macrophages (TAMs). Exosomes are considered as …

Long noncoding RNAs (lncRNAs) or exosomes have recently been shown to play vital
regulatory or communication roles in cancer biology. However, the roles and mechanisms of …

Fibrosis is the final hallmark of pathological remodeling, which is a major contributor to the
pathogenesis of various chronic diseases and aging-related organ failure to fully control …

Background: Clear cell renal cell carcinoma (CCRCC) is characterized by a highly
metastatic potential. The stromal communication between stem cells and cancer cells …

Liver cancer is the second most common cause of cancer-related death worldwide.
Approximately 70–90% of primary liver cancers are hepatocellular carcinoma (HCC) …

While cancer cell proliferation depends on access to extracellular nutrients, inadequate
tumour perfusion means that glucose, amino acids and lipids are often in short supply. To …

Despite advancements in healthcare facilities for diagnosis and treatment, cancer remains
the leading cause of death worldwide. As prevention is always better than cure, efficient …

Growth plate cartilage has limited self-repair ability, leading to poor bone bridge formation
post-injury and ultimately limb growth defects in children. The current corrective surgeries …

Introduction Epithelial-mesenchymal transition (EMT) is a process of transdifferentiation
where epithelial cells attain mesenchymal phenotype to gain invasive properties and thus …