Overcoming cancer therapeutic bottleneck by drug repurposing

Z Zhang, L Zhou, N Xie, EC Nice, T Zhang… - Signal transduction and …, 2020 - nature.com
Ever present hurdles for the discovery of new drugs for cancer therapy have necessitated
the development of the alternative strategy of drug repurposing, the development of old …

Angiogenesis as a hallmark of solid tumors-clinical perspectives

J Majidpoor, K Mortezaee - Cellular Oncology, 2021 - Springer
Background Angiogenesis is a key and early step in tumorigenesis, and is known as a
hallmark of solid tumors and a key promoter of tumor recurrence. Unlike normal tissue …

Tumor angiogenesis and anti‑angiogenic gene therapy for cancer

T Li, G Kang, T Wang, HE Huang - Oncology letters, 2018 - spandidos-publications.com
When Folkman first suggested a theory about the association between angiogenesis and
tumor growth in 1971, the hypothesis of targeting angiogenesis to treat cancer was formed …

Microalgal derivatives as potential nutraceutical and food supplements for human health: A focus on cancer prevention and interception

C Galasso, A Gentile, I Orefice, A Ianora, A Bruno… - Nutrients, 2019 - mdpi.com
Epidemiological studies are providing strong evidence on beneficial health effects from
dietary measures, leading scientists to actively investigate which foods and which specific …

Bioavailability, bioactivity and impact on health of dietary flavonoids and related compounds: an update

A Rodriguez-Mateos, D Vauzour, CG Krueger… - Archives of …, 2014 - Springer
There is substantial interest in the role of plant secondary metabolites as protective dietary
agents. In particular, the involvement of flavonoids and related compounds has become a …

[HTML][HTML] Classification of current anticancer immunotherapies

L Galluzzi, E Vacchelli, JM Bravo-San Pedro, A Buqué… - Oncotarget, 2014 - ncbi.nlm.nih.gov
During the past decades, anticancer immunotherapy has evolved from a promising
therapeutic option to a robust clinical reality. Many immunotherapeutic regimens are now …

The current knowledge concerning solid cancer and therapy

M Najafi, J Majidpoor, H Toolee… - Journal of biochemical …, 2021 - Wiley Online Library
Solid cancers comprise a large number of new cases and deaths from cancer each year
globally. There are a number of strategies for addressing tumors raised from solid organs …

[HTML][HTML] Breast cancer survivorship: a comprehensive review of long-term medical issues and lifestyle recommendations

BI Bodai, P Tuso - The Permanente Journal, 2015 - ncbi.nlm.nih.gov
Long-term survival rates after a diagnosis of breast cancer are steadily rising. This is good
news, but clinicians must also recognize that this brings new challenges to the medical …

Pro-apoptotic and anti-cancer properties of diosgenin: a comprehensive and critical review

G Sethi, MK Shanmugam, S Warrier, M Merarchi… - Nutrients, 2018 - mdpi.com
Novel and alternative options are being adopted to combat the initiation and progression of
human cancers. One of the approaches is the use of molecules isolated from traditional …

[PDF][PDF] RETRACTED: Exosome-derived miR-130a activates angiogenesis in gastric cancer by targeting C-MYB in vascular endothelial cells

H Yang, H Zhang, S Ge, T Ning, M Bai, J Li, S Li… - Molecular Therapy, 2018 - cell.com
Metastasis is a crucial reason for the poor prognosis of gastric cancer. Angiogenesis is
closely associated with tumor invasion and metastasis. Cancer-derived exosomes play an …