Revisiting the mechanisms of ACE inhibitory peptides from food proteins

J Wu, W Liao, CC Udenigwe - Trends in Food Science & Technology, 2017 - Elsevier
Background Angiotensin converting enzyme (ACE) is a key enzyme in the renin angiotensin
system (RAS) responsible for conversion of angiotensin (Ang) I into Ang II, a vasoconstrictor …

[HTML][HTML] Molecular targets of antihypertensive peptides: understanding the mechanisms of action based on the pathophysiology of hypertension

K Majumder, J Wu - International journal of molecular sciences, 2014 - mdpi.com
There is growing interest in using functional foods or nutraceuticals for the prevention and
treatment of hypertension or high blood pressure. Although numerous preventive and …

Molecular interactions, bioavailability, and cellular mechanisms of angiotensin‐converting enzyme inhibitory peptides

H Fan, W Liao, J Wu - Journal of Food Biochemistry, 2019 - Wiley Online Library
Food‐derived angiotensin‐converting enzyme inhibitory (ACEi) peptides have gained
substantial interest as potential alternatives to synthetic drugs in the management of …

Pharmacological treatment and therapeutic perspectives of metabolic syndrome

S Lim, RH Eckel - Reviews in Endocrine and Metabolic Disorders, 2014 - Springer
Metabolic syndrome is a disorder based on insulin resistance. Metabolic syndrome is
diagnosed by a co-occurrence of three out of five of the following medical conditions …

Hypertension and exercise training: evidence from clinical studies

IC Moraes-Silva, CT Mostarda, AC Silva-Filho… - … Disease Prevention and …, 2017 - Springer
Hypertension is a worldwide prevalent disease, mostly manifested as its primary ethiology,
characterized by a chronic, multifactorial, asymptomatic, and usually incurable state. It is …

[HTML][HTML] Unravelling the molecular mechanisms associated with the role of food-derived bioactive peptides in promoting cardiovascular health

SM Martínez-Sánchez, JA Gabaldón-Hernández… - Journal of Functional …, 2020 - Elsevier
Food-derived bioactive peptides (BPs) are nutritionally and functionally important for
regulating some physiological functions in the body; however, there is little information on …

[HTML][HTML] Angiotensin I converting enzyme (ACE) inhibitory activity and antihypertensive effects of rice peptides

J Dong, S Wang, X Yin, M Fang, Z Gong… - Food Science and Human …, 2022 - Elsevier
In this paper, the antihypertension effect of rice peptide (RP) was studied. With
spontaneously hypertensive rats (SHR) and Wistar Kyoto (WKY) as the research objects, RP …

Egg protein-derived bioactive peptides: preparation, efficacy, and absorption

W Liao, F Jahandideh, H Fan, M Son, J Wu - Advances in food and nutrition …, 2018 - Elsevier
The hen's egg is an important protein source of human diet. On average one large egg
contains~ 6 g protein, which contributes to~ 11% of daily protein intake. As a high-quality …

Egg white-derived tripeptide IRW (Ile-Arg-Trp) is an activator of angiotensin converting enzyme 2

W Liao, KS Bhullar, S Chakrabarti… - Journal of agricultural …, 2018 - ACS Publications
Angiotensin converting enzyme 2 (ACE2) plays beneficial roles in the renin angiotensin
aldosterone system. Our previous studies indicated that egg white-derived antihypertensive …

Antihypertensive potential of plant foods: Research progress and prospect of plant-derived angiotensin-converting enzyme inhibition compounds

L Chen, L Wang, G Shu, J Li - Journal of Agricultural and Food …, 2021 - ACS Publications
Global health concerns are clearly evidenced by cardiovascular disease, kidney damage,
and heart attacks. Antihypertensive synthetic drugs, including angiotensin-converting …