[HTML][HTML] Bacterial extracellular vesicles as bioactive nanocarriers for drug delivery: Advances and perspectives

H Liu, Q Zhang, S Wang, W Weng, Y Jing, J Su - Bioactive Materials, 2022 - Elsevier
Nanosized extracellular vesicles derived from bacteria contain diverse cargo and transfer
intercellular bioactive molecules to cells. Due to their favorable intercellular interactions, cell …

Interactions of commensal and pathogenic microorganisms with the intestinal mucosal barrier

EC Martens, M Neumann, MS Desai - Nature Reviews Microbiology, 2018 - nature.com
The intestinal mucosal barrier is composed of epithelial cells that are protected by an
overlying host-secreted mucous layer and functions as the first line of defence against …

Tight junctions as a key for pathogens invasion in intestinal epithelial cells

T Paradis, H Bègue, L Basmaciyan, F Dalle… - International journal of …, 2021 - mdpi.com
Tight junctions play a major role in maintaining the integrity and impermeability of the
intestinal barrier. As such, they act as an ideal target for pathogens to promote their …

Helicobacter pylori: an up-to-date overview on the virulence and pathogenesis mechanisms

HC Sharndama, IE Mba - Brazilian Journal of Microbiology, 2022 - Springer
Helicobacter pylori is an organism associated with ulcer disease and gastric cancer. The
latter is one of the most prevalent malignancies and currently the fourth major cause of …

Desulfovibrio in the Gut: The Enemy within?

SB Singh, A Carroll-Portillo, HC Lin - Microorganisms, 2023 - mdpi.com
Desulfovibrio (DSV) are sulfate-reducing bacteria (SRB) that are ubiquitously present in the
environment and as resident commensal bacteria within the human gastrointestinal tract …

Extracellular vesicles as a novel mediator of interkingdom communication

J Huang, X Wang, Z Wang, L Deng, Y Wang… - Cytokine & Growth …, 2023 - Elsevier
Extracellular vesicles (EVs) are nanosized lipid bilayer-delimited particles secreted from
almost all types of cells including bacteria, mammals and plants, and are presumed to be …

[HTML][HTML] Disruption of the epithelial barrier during intestinal inflammation: Quest for new molecules and mechanisms

S Lechuga, AI Ivanov - Biochimica et Biophysica Acta (BBA)-Molecular Cell …, 2017 - Elsevier
The intestinal epithelium forms a key protective barrier that separates internal organs from
the harmful environment of the gut lumen. Increased permeability of the gut barrier is a …

The extracellular vesicle generation paradox: a bacterial point of view

HM McMillan, MJ Kuehn - The EMBO Journal, 2021 - embopress.org
All bacteria produce secreted vesicles that carry out a variety of important biological
functions. These extracellular vesicles can improve adaptation and survival by relieving …

[HTML][HTML] Extracellular vesicles-mediated interaction within intestinal microenvironment in inflammatory bowel disease

Q Shen, Z Huang, J Yao, Y Jin - Journal of advanced research, 2022 - Elsevier
Background The intestinal tract is a complicated ecosystem with dynamic homeostasis via
interaction of intestine and microbiota. Inflammatory bowel disease (IBD) is chronic intestinal …

Gut bacterial extracellular vesicles: important players in regulating intestinal microenvironment

X Liang, N Dai, K Sheng, H Lu, J Wang, L Chen… - Gut …, 2022 - Taylor & Francis
Intestinal microenvironment dysbiosis is one of the major causes of diseases, such as
obesity, diabetes, inflammatory bowel disease, and colon cancer. Microbiota-based …