A model explaining the dietary-protein-driven post-natal skeletal muscle growth and protein
turnover in the rat is updated, and the mechanisms involved are described, in this narrative …

Duchenne muscular dystrophy (DMD) is a devastating chromosome X-linked disease that
manifests predominantly in progressive skeletal muscle wasting and dysfunctions in the …

Long noncoding RNAs (lncRNAs) play important roles in the spatial and temporal regulation
of muscle development and regeneration. Nevertheless, the determination of their biological …

Skeletal muscle myogenesis is a sophisticated process controlled by genetic and epigenetic
regulators. In animals, one of the key enzymes for the DNA demethylation of 5 …

CCG-1423 is a Rho A pathway inhibitor that has been reported to inhibit Rho/SRF-mediated
transcriptional regulation. Serum response factor and its cofactors, which include ternary …

Pharmacological treatment of Duchenne muscular dystrophy (DMD) with histone
deacetylase inhibitors (HDACi) is currently being tested in clinical trials; however, pre …

Cerebral palsy is a set of common, severe, motor disabilities categorized by a static,
nondegenerative encephalopathy arising in the developing brain and associated with …

Skeletal muscle stem cells (MuSCs) are recognised as functionally heterogeneous. Cranial
MuSCs are reported to have greater proliferative and regenerative capacity when compared …

Duchenne muscular dystrophy is a devastating disease that leads to progressive muscle
loss and premature death. While medical management focuses mostly on symptomatic …

Recent advances in the management of Duchenne muscular dystrophy (DMD), such as
exon skipping and gene therapy, though have reached a clinical stage, the outcome at its …