Treatment of IgA nephropathy: a rapidly evolving field

K El Karoui, FC Fervenza… - Journal of the American …, 2024 - journals.lww.com
The pivotal event in the pathophysiology of IgA nephropathy is the binding of circulating IgA-
containing immune complexes to mesangial cells, with secondary glomerular and …

Novel agents for treating IgA nephropathy

U Kunter, C Seikrit, J Floege - Current Opinion in Nephrology and …, 2023 - journals.lww.com
Novel agents for treating IgA nephropathy : Current Opinion in Nephrology and
Hypertension Novel agents for treating IgA nephropathy : Current Opinion in Nephrology …

The role of copeptin in kidney disease

P Iglesias, RA Silvestre, MJ Fernández-Reyes, JJ Díez - Endocrine, 2023 - Springer
Copeptin is a 39-amino acid glycopeptide that is secreted equimolecularly with arginine-
vasopressin (AVP) from the prepro-hormone AVP in the posterior pituitary. While AVP is a …

External validation of the international prognosis prediction model of IgA nephropathy

L Hu, Y Fang, J Huang, J Liu, L Xu, W He - Renal Failure, 2024 - Taylor & Francis
Abstract Background The International IgA Nephropathy (IgAN) Network developed and
validated two prognostic prediction models for IgAN, one incorporating a race parameter …

Detection of N‑glycoprotein associated with IgA nephropathy in urine as a potential diagnostic biomarker using glycosylated proteomic analysis

J Liu, L Wu, H Gu, M Lu… - Experimental and …, 2023 - spandidos-publications.com
The aim of the present study was to elucidate the potential diagnostic value of urinary N‑
glycoprotein in patients with IgA nephropathy (IgAN) using mass spectrometry (MS). All …

Efficacy of traditional Chinese medicine versus angiotensin-converting enzyme inhibitors, angiotensin receptor blockers, and their combinations in the treatment of …

S Ma, Y Jiang, L Qian, M Wang, S Xu… - Frontiers in …, 2024 - frontiersin.org
Background: IgA nephropathy (IgAN), a condition posing a significant threat to public health,
currently lacks a specific treatment protocol. Research has underscored the potential …

[HTML][HTML] Determining individual glomerular proteinuria and periglomerular infiltration in a cleared murine kidney by a 3-dimensional fast marching algorithm

AMC Böhner, A Effland, AM Jacob, KAM Böhner… - Kidney International, 2024 - Elsevier
Three-dimensional (3D) imaging has advanced basic research and clinical medicine.
However, limited resolution and imperfections of real-world 3D image material often …

Immunosuppressant Agents as Add-On Therapy Failed to Improve the Outcome of Immunoglobulin A Nephropathy with Crescent Score C1

X Bi, Y Yu, S Zhou, Y Zhou, J Zhao, J Xiong - Nephron, 2024 - karger.com
Background The renoprotective benefits of adding immunosuppressant therapy to
corticosteroid (CS) treatment for immunoglobulin A nephropathy (IgAN) patients with less …

[HTML][HTML] Evaluating Progression Risk in Patients with IgAN

DC Cattran, J Floege, R Coppo - Kidney International Reports, 2023 - Elsevier
The highly variable rate of decline in kidney function in patients with immunoglobulin A
nephropathy (IgAN) provides a major clinical challenge. Predicting which patients will …

Evaluating Progression Risk in Patients With Immunoglobulin A Nephropathy

DC Cattran, J Floege, R Coppo - Kidney International Reports, 2023 - kireports.org
The highly variable rate of decline in kidney function in patients with immunoglobulin A
nephropathy (IgAN) provides a major clinical challenge. Predicting which patients will …