[HTML][HTML] Mechanosensitive Piezo1 channel in physiology and pathophysiology of the central nervous system
B Zong, F Yu, X Zhang, Y Pang, W Zhao, P Sun… - Ageing Research …, 2023 - Elsevier
Since the discovery of the mechanosensitive Piezo1 channel in 2010, there has been a
significant amount of research conducted to explore its regulatory role in the physiology and …
significant amount of research conducted to explore its regulatory role in the physiology and …
HLA-B* 27 and ankylosing spondylitis: 50 years of insights and discoveries
MA Khan - Current Rheumatology Reports, 2023 - Springer
Abstract Purpose of Review To commemorate the 50th anniversary of the groundbreaking
discovery of a remarkably strong association between HLA-B* 27 and ankylosing spondylitis …
discovery of a remarkably strong association between HLA-B* 27 and ankylosing spondylitis …
[HTML][HTML] Piezo1 expression in chondrocytes controls endochondral ossification and osteoarthritis development
LJ Brylka, AR Alimy, MEA Tschaffon-Müller, S Jiang… - Bone Research, 2024 - nature.com
Piezo proteins are mechanically activated ion channels, which are required for
mechanosensing functions in a variety of cell types. While we and others have previously …
mechanosensing functions in a variety of cell types. While we and others have previously …
Role of mechanosensitive ion channel Piezo1 in tension-side orthodontic alveolar bone remodeling in rats
Y Du, K Yang - Archives of Oral Biology, 2023 - Elsevier
Objective Orthodontic tooth movement (OTM) is based on alveolar bone remodeling under
mechanical force. In 2010, Piezo1 was identified as a mechanosensitive ion channel that is …
mechanical force. In 2010, Piezo1 was identified as a mechanosensitive ion channel that is …
[HTML][HTML] Mechanotransductive receptor Piezo1 as a promising target in the treatment of fibrosis diseases
Y Xu, Y Huang, X Cheng, B Hu, D Jiang… - Frontiers in Molecular …, 2023 - frontiersin.org
Fibrosis could happen in every organ, leading to organic malfunction and even organ
failure, which poses a serious threat to global health. Early treatment of fibrosis has been …
failure, which poses a serious threat to global health. Early treatment of fibrosis has been …
[HTML][HTML] Disrupted Neural Regeneration in Dry Eye Secondary to Ankylosing Spondylitis—With a Theoretical Link between Piezo2 Channelopathy and Gateway …
B Sonkodi, L Marsovszky, A Csorba, A Balog… - International Journal of …, 2023 - mdpi.com
This study aimed at analyzing the corneal neural regeneration in ankylosing spondylitis
patients using in vivo corneal confocal microscopy in correlation with Langerhans cell …
patients using in vivo corneal confocal microscopy in correlation with Langerhans cell …
Sequence of Events in the Pathogenesis of Axial Spondyloarthritis: A Current Review—2023 SPARTAN Meeting Proceedings
A Srinath, A Nakamura, N Haroon - Current Rheumatology Reports, 2024 - Springer
Abstract Purpose of Review Over the past two decades, significant progress has been made
to untangle the etiology of inflammation and new bone formation (NBF) associated with axial …
to untangle the etiology of inflammation and new bone formation (NBF) associated with axial …
[HTML][HTML] The emerging role of Piezo1 in the musculoskeletal system and disease
Piezo1, a mechanosensitive ion channel, has emerged as a key player in translating
mechanical stimuli into biological signaling. Its involvement extends beyond physiological …
mechanical stimuli into biological signaling. Its involvement extends beyond physiological …
The mechanosensitive ion channel Piezo1 contributes to podocyte cytoskeleton remodeling and development of proteinuria in lupus nephritis.
R Fu, W Wang, Y Huo, L Li, R Chen, Z Lin, Y Tao… - Kidney International, 2024 - Elsevier
Piezo1 functions as a special transducer of mechanostress into electrochemical signals and
is implicated in the pathogenesis of various diseases across different disciplines. However …
is implicated in the pathogenesis of various diseases across different disciplines. However …
[HTML][HTML] The role of mechanically sensitive ion channel Piezo1 in bone remodeling
Y Du, B Xu, Q Li, C Peng, K Yang - Frontiers in Bioengineering and …, 2024 - frontiersin.org
Piezo1 (2010) was identified as a mechanically activated cation channel capable of sensing
various physical forces, such as tension, osmotic pressure, and shear force. Piezo1 …
various physical forces, such as tension, osmotic pressure, and shear force. Piezo1 …