Since the discovery of the mechanosensitive Piezo1 channel in 2010, there has been a
significant amount of research conducted to explore its regulatory role in the physiology and …

Abstract Purpose of Review To commemorate the 50th anniversary of the groundbreaking
discovery of a remarkably strong association between HLA-B* 27 and ankylosing spondylitis …

Piezo proteins are mechanically activated ion channels, which are required for
mechanosensing functions in a variety of cell types. While we and others have previously …

Objective Orthodontic tooth movement (OTM) is based on alveolar bone remodeling under
mechanical force. In 2010, Piezo1 was identified as a mechanosensitive ion channel that is …

Fibrosis could happen in every organ, leading to organic malfunction and even organ
failure, which poses a serious threat to global health. Early treatment of fibrosis has been …

This study aimed at analyzing the corneal neural regeneration in ankylosing spondylitis
patients using in vivo corneal confocal microscopy in correlation with Langerhans cell …

Abstract Purpose of Review Over the past two decades, significant progress has been made
to untangle the etiology of inflammation and new bone formation (NBF) associated with axial …

Piezo1, a mechanosensitive ion channel, has emerged as a key player in translating
mechanical stimuli into biological signaling. Its involvement extends beyond physiological …

Piezo1 functions as a special transducer of mechanostress into electrochemical signals and
is implicated in the pathogenesis of various diseases across different disciplines. However …

Piezo1 (2010) was identified as a mechanically activated cation channel capable of sensing
various physical forces, such as tension, osmotic pressure, and shear force. Piezo1 …