When near-infrared fluorescence meets supramolecular coordination complexes: Challenges and opportunities of metallacycles/metallacages in precision …

Y Xu, Y Dou, Q Li, H Ye, Y Li, S Qiu, X Xiong, J Li… - Coordination Chemistry …, 2023 - Elsevier
In the past decade, the metallacycles/metallacages have attracted unremitting interest in
biomedical fields, yet visual tracking of their in vivo delivery, targeting ability, biodistribution …

Metal‐coordinated supramolecular self‐assemblies for cancer theranostics

J Xu, J Wang, J Ye, J Jiao, Z Liu, C Zhao… - Advanced …, 2021 - Wiley Online Library
Metal‐coordinated supramolecular nanoassemblies have recently attracted extensive
attention as materials for cancer theranostics. Owing to their unique physicochemical …

Self-assembled metallacage with second near-infrared aggregation-induced emission for enhanced multimodal theranostics

Y Qin, X Chen, Y Gui, H Wang, BZ Tang… - Journal of the American …, 2022 - ACS Publications
The construction of supramolecular coordination complexes (SCCs) featuring prominent
cancer theranostic functions is an appealing yet significantly challenging task. In this study …

An NIR Discrete Metallacycle constructed from Perylene Bisimide and Tetraphenylethylene Fluorophores for imaging‐guided cancer Radio‐chemotherapy

Y Ding, Z Tong, L Jin, B Ye, J Zhou, Z Sun… - Advanced …, 2022 - Wiley Online Library
To promote the clinical theranostic performances of platinum‐based anticancer drugs,
imaging capability is urgently desired, and their chemotherapeutic efficacy needs to be …

[HTML][HTML] Rationally designed Ru (ii)-metallacycle chemo-phototheranostic that emits beyond 1000 nm

C Li, Y Xu, L Tu, M Choi, Y Fan, X Chen, JL Sessler… - Chemical …, 2022 - pubs.rsc.org
Ruthenium complexes are emerging as potential complements to platinum drugs. They also
show promise as photo-diagnostic and therapeutic agents. However, most ruthenium …

Dynamic Metallosupramolecular Cages Containing 12 Adaptable Pockets for High-Order Guest Binding Beyond Biomimicry

YH Huang, YL Lu, J Ruan, SP Zheng… - Journal of the …, 2023 - ACS Publications
Molecular recognition lies at the heart of biological functions, which inspires lasting research
in artificial host syntheses to mimic biomolecules that can recognize, process, and transport …

Recent progress in metal-based molecular probes for optical bioimaging and biosensing

Y Ning, GQ Jin, MX Wang, S Gao, JL Zhang - Current Opinion in Chemical …, 2022 - Elsevier
Biological imaging and biosensing from subcellular/cellular level to whole body have
enabled non-invasive visualisation of molecular events during various biological and …

NIR‐II Emissive Ru (II) Metallacycle Assisting Fluorescence Imaging and Cancer Therapy

Y Fan, C Li, S Bai, X Ma, J Yang, X Guan, Y Sun - Small, 2022 - Wiley Online Library
Despite the success of emissive Ruthenium (Ru) agents in biomedicine, problems such as
the visible‐light excitation/emission and single chemo‐or phototherapy modality still hamper …

[HTML][HTML] Strategies to address key challenges of metallacycle/metallacage-based supramolecular coordination complexes in biomedical applications

D Xu, Y Li, S Yin, F Huang - Chemical Society Reviews, 2024 - pubs.rsc.org
Owing to their capacity for dynamically linking two or more functional molecules,
supramolecular coordination complexes (SCCs), exemplified by two-dimensional (2D) …

Bioinorganic supramolecular coordination complexes and their biomedical applications

G Moreno‐Alcántar, A Casini - FEBS letters, 2023 - Wiley Online Library
The field of Bioinorganic Supramolecular Chemistry is an emerging research area including
metal‐based supramolecules resulting from coordination‐driven self‐assembly (CDSA) …