The recent introduction of new-generation immunoassay methods allows the reliable
quantification of structural brain markers in peripheral matrices. Neurofilament light chain …

Neurofilament proteins (Nf) have been validated and established as a reliable body fluid
biomarker for neurodegenerative pathology. This review covers seven Nf isoforms, Nf light …

Importance The potential association of schizophrenia with distinct retinal changes is of
clinical interest but has been challenging to investigate because of a lack of sufficiently large …

Background Major depressive disorder (MDD) is characterized by elevated activity of
peripheral neuro-immune and neuro-oxidative pathways, which may cause neuro-affective …

Neurofilaments (NFs) are not only important for axonal integrity and nerve conduction in
large myelinated axons but they are also thought to be crucial for receptor and synaptic …

Depression is a common neuropsychiatric disorder with long-term recurrent depressed
mood, pain and despair, pessimism and anxiety, and even suicidal tendencies as the main …

Objective: Blood biomarkers of neuronal injury such as neurofilament light (NfL) show
promise to improve diagnosis of neurodegenerative disorders and distinguish …

Background Schizophrenia spectrum disorders (SSD) can be associated with
neurodegenerative processes causing disruption of neuronal, synaptic, or axonal integrity …

We recently demonstrated that patients with ketamine dependence (KD) have increased
serum levels of neurofilament light chain (NfL), a novel marker of active neuroaxonal …

Objective: Schizophrenia, a complex psychiatric disorder, is often associated with cognitive,
neurological and neuroimaging abnormalities. The processes underlying these …