Tackling the emerging threat of antifungal resistance to human health

MC Fisher, A Alastruey-Izquierdo, J Berman… - Nature reviews …, 2022 - nature.com
Invasive fungal infections pose an important threat to public health and are an under-
recognized component of antimicrobial resistance, an emerging crisis worldwide. Across a …

Roles of RNA silencing in viral and non-viral plant immunity and in the crosstalk between disease resistance systems

S Lopez-Gomollon, DC Baulcombe - Nature Reviews Molecular Cell …, 2022 - nature.com
RNA silencing is a well-established antiviral immunity system in plants, in which small RNAs
guide Argonaute proteins to targets in viral RNA or DNA, resulting in virus repression. Virus …

Killing softly: a roadmap of Botrytis cinerea pathogenicity

K Bi, Y Liang, T Mengiste, A Sharon - Trends in plant science, 2023 - cell.com
Botrytis cinerea, a widespread plant pathogen with a necrotrophic lifestyle, causes gray
mold disease in many crops. Massive secretion of enzymes and toxins was long considered …

Foliar application of clay-delivered RNA interference for whitefly control

RG Jain, SJ Fletcher, N Manzie, KE Robinson, P Li… - Nature Plants, 2022 - nature.com
Whitefly (Bemisia tabaci) is a phloem-feeding global agricultural pest belonging to the order
Hemiptera. Foliar application of double-stranded RNA (dsRNA) represents an attractive …

Plant small RNAs: their biogenesis, regulatory roles, and functions

J Zhan, BC Meyers - Annual Review of Plant Biology, 2023 - annualreviews.org
Plant cells accumulate small RNA molecules that regulate plant development, genome
stability, and environmental responses. These small RNAs fall into three major classes …

Technology readiness and overcoming barriers to sustainably implement nanotechnology-enabled plant agriculture

T Hofmann, GV Lowry, S Ghoshal, N Tufenkji… - Nature Food, 2020 - nature.com
Nanotechnology offers potential solutions for sustainable agriculture, including increasing
nutrient utilization efficiency, improving the efficacy of pest management, mitigating the …

RNA-binding proteins contribute to small RNA loading in plant extracellular vesicles

B He, Q Cai, L Qiao, CY Huang, S Wang, W Miao, T Ha… - Nature plants, 2021 - nature.com
Plants use extracellular vesicles (EVs) to transport small RNAs (sRNAs) into their fungal
pathogens and silence fungal virulence-related genes through a phenomenon called 'cross …

Threats posed by the fungal kingdom to humans, wildlife, and agriculture

MC Fisher, SJ Gurr, CA Cuomo, DS Blehert, H Jin… - MBio, 2020 - Am Soc Microbiol
The fungal kingdom includes at least 6 million eukaryotic species and is remarkable with
respect to its profound impact on global health, biodiversity, ecology, agriculture …

Mycotoxin contamination and control strategy in human, domestic animal and poultry: A review

MA Haque, Y Wang, Z Shen, X Li, MK Saleemi… - Microbial …, 2020 - Elsevier
Mycotoxins are secondary metabolites produced mainly by fungi belonging to the genera
Aspergillus, Fusarium, Penicillium, Claviceps, and Alternaria that contaminate basic food …

Spray‐induced gene silencing for disease control is dependent on the efficiency of pathogen RNA uptake

L Qiao, C Lan, L Capriotti, A Ah‐Fong… - Plant Biotechnology …, 2021 - Wiley Online Library
Recent discoveries show that fungi can take up environmental RNA, which can then silence
fungal genes through environmental RNA interference. This discovery prompted the …