The microbiology of asthma
MR Edwards, NW Bartlett, T Hussell… - Nature Reviews …, 2012 - nature.com
Asthma remains an important human disease that is responsible for substantial worldwide
morbidity and mortality. The causes of asthma are multifactorial and include a complex mix …
morbidity and mortality. The causes of asthma are multifactorial and include a complex mix …
The human cathelicidin LL-37 has antiviral activity against respiratory syncytial virus
SM Currie, EG Findlay, BJ McHugh, A Mackellar… - PloS one, 2013 - journals.plos.org
Respiratory syncytial virus is a leading cause of lower respiratory tract illness among infants,
the elderly and immunocompromised individuals. Currently, there is no effective vaccine or …
the elderly and immunocompromised individuals. Currently, there is no effective vaccine or …
Human bocavirus: passenger or pathogen in acute respiratory tract infections?
O Schildgen, A Müller, T Allander… - Clinical microbiology …, 2008 - Am Soc Microbiol
Human bocavirus (HBoV) is a newly identified virus tentatively assigned to the family
Parvoviridae, subfamily Parvovirinae, genus Bocavirus. HBoV was first described in 2005 …
Parvoviridae, subfamily Parvovirinae, genus Bocavirus. HBoV was first described in 2005 …
Antiviral B cell and T cell immunity in the lungs
C Chiu, PJ Openshaw - Nature immunology, 2015 - nature.com
Respiratory viruses are frequent causes of repeated common colds, bronchitis and
pneumonia, which often occur unpredictably as epidemics and pandemics. Despite those …
pneumonia, which often occur unpredictably as epidemics and pandemics. Despite those …
The impact of dual viral infection in infants admitted to a pediatric intensive care unit associated with severe bronchiolitis
N Richard, F Komurian-Pradel… - The Pediatric …, 2008 - journals.lww.com
Objective: To investigate the relevance of dual viral infection in infants with severe
bronchiolitis hospitalized in a short-term unit compared with those in a pediatric intensive …
bronchiolitis hospitalized in a short-term unit compared with those in a pediatric intensive …
Antibiotics for bronchiolitis in children under two years of age
R Farley, GKP Spurling, L Eriksson… - Cochrane Database of …, 2014 - cochranelibrary.com
Background Bronchiolitis is a serious, potentially life‐threatening respiratory illness
commonly affecting babies. It is often caused by respiratory syncytial virus (RSV). Antibiotics …
commonly affecting babies. It is often caused by respiratory syncytial virus (RSV). Antibiotics …
[HTML][HTML] Regulatory T cells expressing granzyme B play a critical role in controlling lung inflammation during acute viral infection
J Loebbermann, H Thornton, L Durant… - Mucosal …, 2012 - Elsevier
The inflammatory response to lung infections must be tightly regulated, enabling pathogen
elimination while maintaining crucial gas exchange. Using recently described “depletion of …
elimination while maintaining crucial gas exchange. Using recently described “depletion of …
[HTML][HTML] Cathelicidins have direct antiviral activity against respiratory syncytial virus in vitro and protective function in vivo in mice and humans
SM Currie, E Gwyer Findlay, AJ McFarlane… - The Journal of …, 2016 - journals.aai.org
Respiratory syncytial virus (RSV) is a leading cause of respiratory tract infection in infants,
causing significant morbidity and mortality. No vaccine or specific, effective treatment is …
causing significant morbidity and mortality. No vaccine or specific, effective treatment is …
[PDF][PDF] Respiratory syncytial virus infects regulatory B cells in human neonates via chemokine receptor CX3CR1 and promotes lung disease severity
D Zhivaki, S Lemoine, A Lim, A Morva, PO Vidalain… - Immunity, 2017 - cell.com
Respiratory syncytial virus (RSV) is the major cause of lower respiratory tract infections in
infants and is characterized by pulmonary infiltration of B cells in fatal cases. We analyzed …
infants and is characterized by pulmonary infiltration of B cells in fatal cases. We analyzed …
Steroids and bronchodilators for acute bronchiolitis in the first two years of life: systematic review and meta-analysis
L Hartling, RM Fernandes, L Bialy, A Milne, D Johnson… - Bmj, 2011 - bmj.com
Objective To evaluate and compare the efficacy and safety of bronchodilators and steroids,
alone or combined, for the acute management of bronchiolitis in children aged less than 2 …
alone or combined, for the acute management of bronchiolitis in children aged less than 2 …