Treatment with High-Dose Prednisolone in Vigabatrin-Refractory Infantile Spasms

W Al-Shehhi, V Chau, J Boyd, C Snead… - Canadian Journal of …, 2022 - cambridge.org
Objectives: This research aimed to study the short-term seizure outcomes following
treatment with 8 mg/kg/day prednisolone in children with infantile spasms (IS) refractory to …

Brazilian experts' consensus on the treatment of infantile epileptic spasm syndrome in infants

LPB Sampaio, AMM Henriques-Souza… - Arquivos de Neuro …, 2023 - SciELO Brasil
Background Infantile epileptic spasms syndrome (IESS) is a rare but severe condition
affecting children early and is usually secondary to an identifiable brain disorder. It is related …

Safety and effectiveness of oral methylprednisolone therapy in comparison with intramuscular adrenocorticotropic hormone and oral prednisolone in children with …

HM Zhu, CH Yuan, MQ Luo, XL Deng, S Huang… - Frontiers in …, 2021 - frontiersin.org
Background and Purpose: To assess the safety and effectiveness of oral
methylprednisolone (oMP) in comparison with intramuscular adrenocorticotropic hormone …

Factors predictive of prognosis of infantile spasms. A retrospective study in a low-income country

RB Abdelaziz, AB Chehida, M Lamouchi… - Archives de …, 2019 - Elsevier
Purpose To describe the management of infants with epileptic spasms (ESs) in a low-
income country and identify factors predictive of their prognosis. Material and methods We …

Steroids in Infantile Spasms Syndrome: Another Trial, Another Drug, Another Dose, What's Next?

R Whitney, P Jain - Annals of Indian Academy of Neurology, 2022 - journals.lww.com
Annals of Indian Academy of Neurology¦ Volume 25¦ Issue 5¦ September-October 2022 800
more responsive to treatment. Comparing the use of oral dexamethasone to other forms of …

Epileptic spasms: A South African overview of aetiologies, interventions, and outcomes

SV Raga, F Essajee, R Solomons… - … Medicine & Child …, 2023 - Wiley Online Library
Aim To better understand the aetiologies of epileptic spasms in infants, as well as the safety
and efficacy of high dose corticosteroids in tuberculosis and human immunodeficiency virus …

[引用][C] 婴儿痉挛遗传学研究与诊治

王纪文 - 中国实用儿科杂志, 2015

Synthetic ACTH is not superior to prednisolone for infantile spasms: randomized clinical trials and tribulations

JR Mytinger, PR Camfield - Pediatric neurology, 2015 - pedneur.com
There are only three therapies with greater than class IV evidence to support their use for the
treatment of infantile spasmsdadrenocorticotropic hormone (ACTH), vigabatrin, and oral …

Management of infantile spasms: an updated review

M Iype, KG Koshy - International Journal of Epilepsy, 2020 - thieme-connect.com
Infantile spasms remain the most challenging of the epileptic encephalopathies of
childhood. Infantile spasms are classified as an epileptic encephalopathy, as the adverse …

Clinical profile of children with West syndrome: a retrospective chart review

VK Gehlawat, V Arya, H Bhardwaj… - Journal of Family …, 2021 - journals.lww.com
Background: This study was intended to document the clinical profile and treatment outcome
of West syndrome in children attending a tertiary care centre in Northern India. Methods …