shRNA-mediated gene silencing of HDAC11 empowers CAR-T cells against prostate cancer

H Zhang, J Yao, I Ajmal, MA Farooq… - Frontiers in …, 2024 - frontiersin.org
Epigenetic mechanisms are involved in several cellular functions, and their role in the
immune system is of prime importance. Histone deacetylases (HDACs) are an important set …

[HTML][HTML] The pan-cancer analysis uncovers the prognostic and immunotherapeutic significance of CD19 as an immune marker in tumor

L Wei, J Meng, D Xiang, Q Yang, Y Zhou… - … Journal of General …, 2024 - ncbi.nlm.nih.gov
Background The specific cytotoxic effects of anti-CD19 chimeric antigen receptor (CAR) T-
cell therapy have led to impressive outcomes in individuals previously treated for B-cell …