Neurodegenerative diseases are conventionally demarcated as disorders with selective loss
of neurons. Conventional as well as newer molecules have been tested but they offer just …

Dietary interventions have emerged as effective environmental inducers of brain plasticity.
Among these dietary interventions, we here highlight the impact of caloric restriction (CR: a …

Lipid metabolism is fundamental for brain development and function, but its roles in normal
and pathological neural stem cell (NSC) regulation remain largely unexplored. Here, we …

Fatty acids (FAs) are typically associated with structural and metabolic roles, as they can be
stored as triglycerides, degraded by β-oxidation or used in phospholipids' synthesis, the …

Neurodegeneration is a progressive loss of neuronal cells in certain regions of the brain.
Most of the neurodegenerative disorders (NDDs) share the communal characteristic such as …

Background: Omega-3 polyunsaturated fatty acids (n-3 PUFA) are structural components of
the brain and are indispensable for neuronal membrane synthesis. Along with decline in …

Brain is a central and pivotal organ of human body containing the highest lipids content next
to adipose tissue. It works as a monitor for the whole body and needs an adequate supply of …

Obesity and metabolic syndrome are associated with cognitive decline and dementia.
Palmitic acid (PA) is increased in the cerebrospinal fluid of obese patients with cognitive …

Lipids play crucial roles in cell signaling and various physiological processes, especially in
the brain. Impaired lipid metabolism in the brain has been implicated in neurodegenerative …

Polyunsaturated fatty acids (PUFAs) are found in abundance in the nervous system. They
perform significant functions for example boosting synaptogenesis, neurogenesis, inducing …