Real-time single-molecule imaging of transcriptional regulatory networks in living cells

DW Hwang, A Maekiniemi, RH Singer… - Nature Reviews …, 2024 - nature.com
Gene regulatory networks drive the specific transcriptional programmes responsible for the
diversification of cell types during the development of multicellular organisms. Although our …

[HTML][HTML] Studying chromatin epigenetics with fluorescence microscopy

AI Stepanov, ZV Besedovskaia, MA Moshareva… - International Journal of …, 2022 - mdpi.com
Epigenetic modifications of histones (methylation, acetylation, phosphorylation, etc.) are of
great importance in determining the functional state of chromatin. Changes in epigenome …

Live-cell imaging probes to track chromatin modification dynamics

Y Sato, M Nakao, H Kimura - Microscopy, 2021 - academic.oup.com
The spatiotemporal organization of chromatin is regulated at different levels in the nucleus.
Epigenetic modifications such as DNA methylation and histone modifications are involved in …