Metastatic malignant melanoma is an incurable disease with a median survival of 8.5
months and a probability of surviving 5 years after the diagnosis of less than 5%. To date, no …

BACKGROUND AND PURPOSE Nephrotoxicity is the principal dose‐limiting factor for
cisplatin chemotherapy and is primarily associated with proximal tubular epithelial cells …

Chemotherapy has remained the mainstay for the treatment of multiple types of cancers. In
particular, topical use of chemotherapy has been used for skin cancers. Though effective …

This prospective, nonrandomized multicentre, phase III study compared best supportive care
(BSC) alone with cisplatin, vindesine and dacabazine-based (CVD) chemotherapy and BSC …

Das maligne Melanom belegt bei Malignomen in Europa und den USA die Plätze 6 bei den
Männern und 7 bei den Frauen. In den frühen Stadien ist eine Heilung in der Regel möglich …

Treosulfan w leczeniu zaawansowanego raka jajnika i przerzutowego czerniaka skóry oraz
gałki ocznej Page 1 127 www.opk.viamedica.pl Krzysztof Krzemieniecki1, Aneta L. Zygulska2 …

患者男, 1974 年8 月出生, 2003 年8 月发现右侧腹壁一花生米大小黑痣, 遂行局部扩大切除,
术后未行特殊治疗. 2005 年9 月因右侧腋窝肿块就诊, 当时检查局部无疼痛, 周围皮肤无红肿 …

Treosulfan is an alkylating agent with mild toxicity and proven clinical activity in the treatment
of advanced ovarian cancer, cutaneous and uveal melanoma. According to authors …

The ability of a compound to exert its antineoplastic activity is determined by the amount of
its accumulation inside the cell, a process largely dependent on the transporter proteins …

Zusammenfassend gelang es in unseren Arbeiten, zum einen weiterführende Daten
bezüglich verschiedener Serummarker in tumorfreien Stadien zu gewinnen, zum anderen …