Ischemic stroke is caused primarily by an interruption in cerebral blood flow, which induces
severe neural injuries, and is one of the leading causes of death and disability worldwide …

Electrophiles and reactive oxygen species (ROS) play a major role in modulating cellular
defense mechanisms as well as physiological functions, and intracellular signaling …

Recent research on the gut microbiome has revealed the influence of gut microbiota (GM)
on ischemic stroke pathogenesis and treatment outcomes. Alterations in the diversity …

Plasma medicine comprises the application of physical plasma directly on or in the human
body for therapeutic purposes. Three most important basic plasma effects are relevant for …

Abstract NF-E2-related factor 2 (Nrf2) protein is a basic-region leucine zipper transcription
factor that defends against endogenous or exogenous stressors. By inducing several …

Vitiligo is a common chronic acquired pigmentation disorder characterized by loss of
pigmentation. Among various hypotheses proposed for the pathogenesis of vitiligo, oxidative …

Nrf2 is a transcription factor that stimulates the expression of genes which have antioxidant
response element-like sequences in their promoter. Nrf2 is a cellular protector, and this …

Polyphenols are characterised structurally by two or more hydroxyl groups attached to one
or more benzene rings, and provide the taste and colour characteristics of fruits and …

The morbidity rate of myocardial ischemia and reperfusion has increased in modern society,
and oxidative stress plays a critical role in the pathological process. Nuclear factor E2 …

The production of reactive species is an inevitable by-product of metabolism and thus, life
itself. Since reactive species are able to damage cellular structures, especially proteins, as …